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Showing 141-146 of 146 results
  1. From genetics to the clinic: a translational perspective on follicular lymphoma

    Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still considered to be incurable. In recent years, whole-exome...

    Sarah Huet, Pierre Sujobert, Gilles Salles in Nature Reviews Cancer
    Article 09 February 2018
  2. Methods for High-throughput Drug Combination Screening and Synergy Scoring

    Gene products or pathways that are aberrantly activated in cancer but not in normal tissue hold great promises for being effective and safe...
    Liye He, Evgeny Kulesskiy, ... **g Tang in Cancer Systems Biology
    Protocol 2018
  3. Lapatinib resistance in HER2+ cancers: latest findings and new concepts on molecular mechanisms

    In the era of new and mostly effective molecular targeted therapies, human epidermal growth factor receptor 2 positive (HER2+) cancers are still...

    Hui** Shi, Weili Zhang, ... Min Jiang in Tumor Biology
    Article 10 October 2016
  4. Phosphoinositide 3-Kinase

    Honyin Chiu, Lomon So, David A. Fruman in Encyclopedia of Signaling Molecules
    Living reference work entry 2016
  5. PI3K isoform-selective inhibitors: next-generation targeted cancer therapies

    The pivotal roles of phosphatidylinositol 3-kinases (PI3Ks) in human cancers have inspired active development of small molecules to inhibit these...

    **ang Wang, Jian Ding, Ling-hua Meng in Acta Pharmacologica Sinica
    Article 14 September 2015
  6. Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms

    Myeloproliferative neoplasms (MPN) are a diverse group of chronic hematological disorders that involve unregulated clonal proliferation of white...

    Ruchi Pandey, Reuben Kapur in Molecular Cancer
    Article Open access 11 June 2015
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