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Perioperative Assessment and Management of Patients with Sleep Disorders
In the United States, about 60,000 patients receive general anesthesia for surgery per day. The most important postoperative cardiac, neurologic, and...
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Clinical and electrophysiological characteristics of respiratory onset amyotrophic lateral sclerosis: a single-centre study
BackgroundWe compared the clinical characteristics of patients with respiratory, bulbar and limb onset amyotrophic lateral sclerosis (ALS) who...
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Psychiatric Disorders in Animal Models of Depression
1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) demonstrates significant neuroprotective, antioxidant, and antidepressant-like activity in rodents....
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Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma
BackgroundThis study aimed to validate whether infusion of GD2-specific fourth-generation safety-designed chimeric antigen receptor (4SCAR)-T cells...
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Male versus female inflammatory response after brain death model followed by ex vivo lung perfusion
BackgroundEx vivo lung perfusion (EVLP) is a useful tool for assessing lung grafts quality before transplantation. Studies indicate that donor sex is...
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Cytauxzoon europaeus infections in domestic cats in Switzerland and in European wildcats in France: a tale that started more than two decades ago
BackgroundCytauxzoon spp. infection is believed to be a newly emerging tick-borne disease in felids in Europe, with three species of the...
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Identification and genetic characterization of an isolate of bovine adenovirus 7 from the United States, a putative member of a new species in the genus Atadenovirus
The bovine adenovirus 7 (BAdV-7) isolate SD18-74 was recovered from lung tissue of calves in South Dakota. The 30,043-nucleotide (nt) genome has the...
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The implication of infection with respiratory syncytial virus in pediatric recurrent wheezing and asthma: knowledge expanded post-COVID-19 era
BackgroundRespiratory syncytial virus (RSV) infection has been identified to serve as the primary cause of acute lower respiratory infectious...
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Extraintestinal Helminths
Helminths infesting the liver of camels are mainly the trematodes, Fasciola hepatica, F. gigantica, Dicrocoelium dendriticum, and less often...
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Role of Synbiotics in Gastrointestinal Disorders
A sophisticated microbiome has colonized the human gastrointestinal tract. In addition to being symbiotic, intestinal bacteria coevolve with their...
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The golden key to open mystery boxes of SMARCA4-deficient undifferentiated thoracic tumor: focusing immunotherapy, tumor microenvironment and epigenetic regulation
SMARCA4-deficient undifferentiated thoracic tumor is extremely invasive. This tumor with poor prognosis is easily confused with SMARCA4-deficent...
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Citrullinated Histone H3 as a Biomarker in Sepsis and Critical Care
Sepsis occurs when the body’s response to these chemicals is unbalanced and changes are triggered that can damage multiple organ systems. Histones...
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Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome
Two variants in the ubiquitously expressed NHLRC2 gene have been reported to cause a lethal fibrotic cerebropulmonary disease termed fibrosis,...
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Community acquired Acinetobacter baumannii in pediatric patients under 1 year old with a clinical diagnosis of whoo** cough in Lima, Peru
ObjectiveThis study aimed to determine the prevalence of A. baumannii in children aged less than 1 year admitted with a clinical diagnosis of...
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Prognostic variables for conditional survival in patients with esophageal squamous cell carcinoma who underwent minimally invasive surgery
BackgroundEsophageal squamous cell carcinoma (ESCC) survival is mainly reported at the time of treatment. Conditional survival is another prognostic...
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Targeting Molecular and Cellular Mechanisms in Respiratory Syncytial Virus (RSV) Infection
RSV is a negatively stranded RNA virus from the paramyxovirus family. It sprouts from the apical surface of epithelial cells and creates a...
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Why do patients with cancer die?
Cancer is a major cause of global mortality, both in affluent countries and increasingly in develo** nations. Many patients with cancer experience...
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Intelligent alert system for predicting invasive mechanical ventilation needs via noninvasive parameters: employing an integrated machine learning method with integration of multicenter databases
The use of invasive mechanical ventilation (IMV) is crucial in rescuing patients with respiratory dysfunction. Accurately predicting the demand for...
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Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation
Endotoxin shock remains one of the major causes of mortality worldwide. Pyruvate dehydrogenase kinase (PDK) 2 is an important regulatory enzyme...
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Clinical Presentation and Therapy of Semilunar Valve and Aortic Arch Anomalies
The following semilunar valve defects and aortic arch anomalies are called simple defects because there is a single problem that can be well...