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Therapeutic Potential of Umbilical Cord MSC in Crohn’s Disease Is Related to Regulation of the Relative Content and Function of Th17 Lymphocytes
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are chronic and relapsing autoimmune disorders with active...
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Circulating CD8+CD122+ T cells as a prognostic indicator of pancreatic cancer
PurposeThe distribution of tissue infiltrating lymphocytes has been shown to affect the prognosis of patients with pancreatic cancer in some previous...
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In Vitro Evaluation of Cancer Cell Immunogenicity and Antigen-Specific T-Cell Cytotoxicity by Flow Cytometry
A cardinal principle of oncoimmunology is that cancer cells can be eliminated by tumor-infiltrating cytotoxic CD8 T lymphocytes. This has been widely...
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Retraction Note to: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Divergent immune microenvironments in two tumor nodules from a patient with mismatch repair-deficient prostate cancer
Patients with prostate cancer (PC) generally do not respond favorably to immune checkpoint inhibitors, which may be due to a low abundance of...
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The role of immune checkpoint receptors in the malignant phenotype of cutaneous T cell lymphoma
Immune checkpoint receptors (ICR) modulate the immune response and are critical hubs for immunotherapy. However, data on their role in T lymphoid...
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Introduction to Cancer Immunology
Cancer immunology is among the most important disciplines of cellular and molecular immunology, and it has progressed significantly in the last...
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Clinicopathological significance and prognostic role of LAG3 + tumor-infiltrating lymphocytes in colorectal cancer; relationship with sidedness
BackgroundIt is well-documented that the interplay between tumor-infiltrating lymphocytes (TILs) and tumor cells is a major determining factor in...
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Study of the effect of intestinal immunity in neonatal piglets coinfected with porcine deltacoronavirus and porcine epidemic diarrhea virus
Porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhea virus (PEDV) have often been detected simultaneously in piglets with coronavirus...
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PD-1 receptor outside the main paradigm: tumour-intrinsic role and clinical implications for checkpoint blockade
Blocking the inhibitory receptor PD-1 on antitumour T lymphocytes is the main rationale underlying the clinical successes of cancer immunotherapies...
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Immunophenotype of lymphocytes and real-world outcome of COVID-19 infection in children with hematology and oncology
BackgroundPatients with immunocompromise were suspected to encounter a high risk for severe coronavirus disease 2019 (COVID-19) infection on early...
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Immunotherapy of Solid Tumors Based on Neoantigen Vaccines
The term “cancer immunotherapy” refers to a broad spectrum of therapeutic modalities that use the immune system to trigger specific anticancer immune...
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Retrogenic Color-Barcoding for Fate Map** of Single Innate Lymphocytes
Lymphocyte fate map** using single-cell transfers has been used to study T and B cell differentiation. Recently, retrogenic color-barcoding has...
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Causal effects between circulating immune cells and heart failure: evidence from a bidirectional Mendelian randomization study
BackgroundHeart failure (HF) is a prevalent cardiac condition characterized by high mortality and morbidity rates. Immune cells play a pivotal role...
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ISG15 targets glycosylated PD-L1 and promotes its degradation to enhance antitumor immune effects in lung adenocarcinoma
BackgroundImmunocheckpoint inhibitors (ICIs) have been widely used in the clinical treatment of lung cancer. Although clinical studies and trials...
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Theiler’s murine encephalomyelitis virus infection of astrocytes induces the expression of chemokines which attract activated but not resting T lymphocytes
In this article, we studied the production of the chemokine CXCL9, also termed Mig (monokine induced by gamma interferon) by cultured SJL/J mouse...
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Adoptive Immunotherapy Is a Successful Step into Bright Future
Background. The review aims to present the major advances of adoptive cell immunotherapy from the emergence of antitumor immunotherapy to future...
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Correction to: TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity
The original article was published with an error. In Figure 9b there are 3 typographical errors: instead of the Greek mu letter it shows the...
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Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes
CRISPR-mediated genome editing of primary human lymphocytes is typically carried out via electroporation, which can be cytotoxic, cumbersome and...
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Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer
AimsImmune checkpoint inhibitor (ICI) therapy has become a viable treatment strategy in bladder cancer. However, treatment responses vary, and...
