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1. Identification of ferroptosis-related signature with potential implications in prognosis and immunotherapy of renal cell carcinoma

   Develo** individualized therapies for different renal cell carcinoma patients is pivotal for improving the efficacy of immunotherapy. It has been...

   Lingfeng Liu, Huan **, ... Zhengzhi Zou in Apoptosis

   Article 26 August 2022
   

2. ZEB family is a prognostic biomarker and correlates with anoikis and immune infiltration in kidney renal clear cell carcinoma

   Background

   Zinc finger E-box binding homEeobox 1 (ZEB1) and ZEB2 are two anoikis-related transcription factors. The mRNA expressions of these two...

   Sheng Lin, Qi Chen, ... Ting Zhu in BMC Medical Genomics

   Article Open access 05 June 2024
   

3. Clinical outcome predictors for metastatic renal cell carcinoma: a retrospective multicenter real-life case series

   Over the last decades, the therapeutic armamentarium of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of...

   Mimma Rizzo, Gaetano Pezzicoli, ... Silvana Quaglini in BMC Cancer

   Article Open access 05 July 2024
   

4. PTEN loss confers sensitivity to rapalogs in clear cell renal cell carcinoma

   Rapalogs (everolimus and temsirolimus) are allosteric mTORC1 inhibitors and approved agents for advanced clear cell renal cell carcinoma (ccRCC),...

   **ao-lian Liu, Gui-ming Zhang, ... Yi-lei Li in Acta Pharmacologica Sinica

   Article 14 February 2022
   

5. The immunoreactivity of GLI1 and VEGFA is a potential prognostic factor in kidney renal clear cell carcinoma

   Kidney renal clear cell carcinoma (KIRC) is the most common type of kidney cancer and its pathogenesis is strongly associated with VHL–HIF–VEGF...

   Anna Kotulak-Chrzaszcz, Jacek Kiezun, ... Piotr M. Wierzbicki in BMC Cancer

   Article Open access 14 November 2023
   

6. Glycolysis-related biomarker TCIRG1 participates in regulation of renal cell carcinoma progression and tumor immune microenvironment by affecting aerobic glycolysis and AKT/mTOR signaling pathway

   Background

   Renal cell carcinoma (RCC) is a hypermetabolic disease. Abnormal up-regulation of glycolytic signaling promotes tumor growth, and...

   Sichen Di, Min Gong, ... **ngang Cui in Cancer Cell International

   Article Open access 30 August 2023
   

7. The role of spleen volume change in predicting immunotherapy response in metastatic renal cell carcinoma

   Introduction

   Resistance to immune checkpoint inhibitors (ICI) is a significant issue in metastatic renal cell carcinoma (mRCC), as it is in the...

   Volkan Aslan, Atiye Cenay Karabörk Kılıç, ... Nuriye Özdemir in BMC Cancer

   Article Open access 30 October 2023
   

8. The intrarenal landscape of T cell receptor repertoire in clear cell renal cell cancer

   Background

   Clear cell renal cell cancer (ccRCC) is accompanied by T-cell infiltration. In this study, we sought to determine the difference in T-cell...

   Wei Zhang, Qian Zhang, ... Kejia Wang in Journal of Translational Medicine

   Article Open access 03 December 2022
   

9. Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma

   Purpose

   Sunitinib is a recommended drug for metastatic renal cell carcinoma (RCC). However, the therapeutic potential of sunitinib is impaired by...

   Tingyu Liu, **n Yue, ... Ran-Yi Liu in Cellular Oncology

   Article 23 February 2024
   

10. Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma

    Background

    Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence, outcomes, molecular alterations and treatment efficacy; however,...

    Huiyang Yuan, **n Qin, ... Dawei Xu in Biology of Sex Differences

    Article Open access 11 July 2023
    

11. The role of natural products versus miRNA in renal cell carcinoma: implications for disease mechanisms and diagnostic markers

    Natural products are chemical compounds produced by living organisms. They are isolated and purified to determine their function and can potentially...

    Abdullah Ayed in Naunyn-Schmiedeberg's Archives of Pharmacology

    Article 01 May 2024
    

12. Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application

    Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the most common malignancies worldwide. The unremarkable...

    Mingyang Li, Lei Li, ... **aonan Chen in Molecular Cancer

    Article Open access 21 February 2023
    

13. Construction and validation of a ferroptosis-related long noncoding RNA signature in clear cell renal cell carcinoma

    Background

    Clear cell renal cell carcinoma (ccRCC) is characterized by the accumulation of lipid-reactive oxygen species. Ferroptosis, due to the...

    Zhenpeng Zhu, Cuijian Zhang, ... Liqun Zhou in Cancer Cell International

    Article Open access 14 September 2022
    

14. Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family

    Background

    Annexins are a family of proteins involved in a wide variety of cellular processes such as inflammation, proliferation, differentiation,...

    Li-Hui Wang, Bo Cao, ... Bao-** Qiao in BMC Cancer

    Article Open access 18 July 2023
    

15. Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma

    Background

    Clear cell renal cell carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy and is correlated with metabolic...

    Hansen Lin, Liangmin Fu, ... Jiazheng Cao in Journal of Translational Medicine

    Article Open access 23 May 2023
    

16. PDCD5 inhibits progression of renal cell carcinoma by promoting T cell immunity: with the involvement of the HDAC3/microRNA-195-5p/SGK1

    Background

    Epigenetics exerts a vital role in the onset and development of renal cell carcinoma (RCC). Mounting evidence has shed light on the...

    Shu-cheng Liu, Li-bo Chen, ... **n-sheng Lu in Clinical Epigenetics

    Article Open access 20 October 2022
    

17. LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma

    Background

    Distant metastasis is the major cause of clear cell renal cell carcinoma (ccRCC)-associated mortality. However, molecular mechanisms...

    Yanliang Wang, Yu Chen Feng, ... Feng-Min Shao in Journal of Experimental & Clinical Cancer Research

    Article Open access 26 August 2022
    

18. Molecular mechanism of circRNAs in drug resistance in renal cell carcinoma

    Renal cell carcinoma (RCC) is one of the most common malignant tumors with a poor response to radiotherapy and chemotherapy. The advent of molecular...

    Shuang Qin, Yuting Wang, ... Qi Lv in Cancer Cell International

    Article Open access 24 November 2022
    

19. Squamous Cell Carcinoma Predisposition Pathophysiology, Diagnosis, and Treatment

    Squamous Cell Carcinoma (SCC) is a prevalent form of skin and oral cancer, characterized by the uncontrolled growth of abnormal squamous cells in the...

    S. Gowtham Kumar, G. Karthikeyan, ... K. Langeswaran in Handbook of Oncobiology: From Basic to Clinical Sciences

    Living reference work entry 2023
    

20. Intratumoral fibrosis and patterns of immune infiltration in clear cell renal cell carcinoma

    Background

    Intratumoral fibrosis was positively correlated with histological grade of renal clear cell carcinoma (ccRCC) and intratumoral...

    Songchen Han, Wenbo Yang, ... Tao Xu in BMC Cancer

    Article Open access 16 June 2022