Search
Search Results
-
Down-regulation Synaptic Vesicle Protein 2A in the Anterior Temporal Neocortex of Patients with Intractable Epilepsy
Synaptic vesicle protein 2A (SV2A) involvement has been reported in the animal models of epilepsy. The aim of this study was to investigate the...
-
Comparative study of five antiepileptic drugs on a translational cognitive measure in the rat: relationship to antiepileptic property
RationaleAntiepileptic drugs (AEDs) have been available for many years; yet, new members of this class continue to be identified and developed due to...
-
Brivaracetam (UCB 34714)
Brivaracetam (UCB 34714) is chemically related to levetiracetam (LEV, Keppra®). It possesses a binding affinity for the synaptic vesicle protein 2A...
-
-
Valproic acid: Second generation
The manuscript focuses on structure-activity relationship studies of CNS-active compounds derived from valproic acid (VPA) that have the potential to...
-
Molecular targets for antiepileptic drug development
This review considers how recent advances in the physiology of ion channels and other potential molecular targets, in conjunction with new...