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Virophages, polintons, and transpovirons: a complex evolutionary network of diverse selfish genetic elements with different reproduction strategies
BackgroundRecent advances of genomics and metagenomics reveal remarkable diversity of viruses and other selfish genetic elements. In particular,...
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Hidden evolutionary complexity of Nucleo-Cytoplasmic Large DNA viruses of eukaryotes
BackgroundThe Nucleo-Cytoplasmic Large DNA Viruses (NCLDV) constitute an apparently monophyletic group that consists of at least 6 families of...
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A comparative analysis on the synonymous codon usage pattern in viral functional genes and their translational initiation region of ASFV
The synonymous codon usage pattern of African swine fever virus (ASFV), the similarity degree of the synonymous codon usage between this virus and...
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Introduction: The Structural Basis of Virus Function
Viruses may be regarded as dynamic nucleoprotein assemblies capable of assisted multiplication within cells, and of propagation between cells and... -
Tick-borne viruses in Europe
The aim of this review is to present briefly background information on 27 tick-borne viruses (“tiboviruses”) that have been detected in Europe, viz...
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Viruses with Single-Stranded, Positive-Sense RNA Genomes
Eight virus families whose members infect vertebrates are currently known to possess single-stranded, positive-sense RNA genomes: the families... -
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Genetic characterisation of African swine fever viruses from recent and historical outbreaks in Sardinia (1978–2009)
Three discrete regions of the African swine fever virus (ASFV) were analysed in the genomes of a wide range of isolates collected from wild and...
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First detection of African Swine Fever Virus in Ornithodoros porcinus in Madagascar and new insights into tick distribution and taxonomy
BackgroundAfrican Swine Fever Virus has devastated more than the half of the domestic pig population in Madagascar since its introduction, probably...
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A proposal to change existing virus species names to non-Latinized binomials
A proposal has been posted on the ICTV website (2011.001aG.N.v1.binomial_sp_names) to replace virus species names by non-Latinized binomial names...
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A novel TLR3 inhibitor encoded by African swine fever virus (ASFV)
African swine fever virus (ASFV) encodes proteins that manipulate important host antiviral mechanisms. Bioinformatic analysis of the ASFV genome...
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Remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus
Heterocapsa circularisquama DNA virus (HcDNAV; previously designated as HcV) is a giant virus (girus) with a ~356-kbp double-stranded DNA (dsDNA)...
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Horizontal Gene Transfers with or without Cell Fusions in All Categories of the Living Matter
This article reviews the history of widespread exchanges of genetic segments initiated over 3 billion years ago, to be part of their life style, by... -
The African swine fever virus lectin EP153R modulates the surface membrane expression of MHC class I antigens
We have modeled a 3D structure for the C-type lectin domain of the African swine fever virus protein EP153R, based on the structure of CD69, CD94 and...
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Arboviral Encephalitides: Transmission, Emergence, and Pathogenesis
Arthropod-borne viruses (arboviruses) are of paramount concern as a group of pathogens at the forefront of emerging and re-emerging diseases....
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Eukaryotic large nucleo-cytoplasmic DNA viruses: Clusters of orthologous genes and reconstruction of viral genome evolution
BackgroundThe Nucleo-Cytoplasmic Large DNA Viruses (NCLDV) comprise an apparently monophyletic class of viruses that infect a broad variety of...
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Molecular characterisation of African swine fever viruses from Nigeria (2003–2006) recovers multiple virus variants and reaffirms CVR epidemiological utility
Samples collected from wild and domestic suids in Nigeria, over a 3-year period (2003–2006), were evaluated for African swine fever (ASF) virus...
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African Swine Fever Virus
African swine fever virus (ASFV) is a large, intracytoplasmically-replicating DNA arbovirus and the sole member of the family Asfarviridae. It is the... -
Apoptosis in porcine macrophages infected in vitro with African swine fever virus (ASFV) strains with different virulence
African swine fever virus (ASFV) replicates in porcine macrophages. Since modulation of cell death by ASFV strains of different virulence is poorly...
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Ascoviruses: Superb Manipulators of Apoptosis for Viral Replication and Transmission
Ascoviruses are members of a recently described new family ( Ascoviridae ) of large double-stranded DNA viruses that attack immature stages of...