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Effect of PLGA raw materials on in vitro and in vivo performance of drug-loaded microspheres
Poly(lactide- co -glycolide) and poly(lactic-co-glycolic acids) (PLGAs) play a critical role in the development of commercial long-acting injectable...
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Scaffold-Mediated Drug Delivery for Enhanced Wound Healing: A Review
Wound healing is a complex physiological process involving coordinated cellular and molecular events aimed at restoring tissue integrity. Acute...
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Cyclodextrins and their potential applications for delivering vitamins, iron, and iodine for improving micronutrient status
Cyclodextrins (CDs) have been investigated as potential biopolymeric carriers that can form inclusion complexes with numerous bioactive ingredients....
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Fucoidan-Based Nanoparticles for the Targeted Delivery of Anticancer Agents
Recently, remarkable progress has been witnessed in the nanoparticles-based delivery of anticancer agents to improve therapeutic outcomes. Various...
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Biodegradable Packaging Materials and Techniques to Improve Their Performance
The most used materials for the development of food packaging are petroleum-based polymers. Despite the advantages that synthetic polymers have, the...
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Surface Properties of Polysaccharides
Polysaccharides are sugar derivative polymers with high natural abundance existing in microorganisms, algae, plants, insects, and animals, where they...
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Bioengineering and Bioinformatic Approaches to Study Extracellular Matrix Remodeling and Cancer–Macrophage Crosstalk in the Breast Tumor Microenvironment
Tumor-associated macrophages (TAMs) are one of the most abundant cell types in the breast tumor microenvironment. TAMs are characterized by...
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Nanoparticles in Chronic Respiratory Diseases
Small particles ranging from 1 to 100 nm that have significant surface energy may be termed as nanoparticles. These nano-sized particles enable...
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Chitosan-Based Nanocomposite as Targeted Drug Delivery Carrier
Chitosan, a biopolymer, has versatile physicochemical and biological/pharmacological properties which are treasury for the pharmaceutical field....
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Biologics and Vaccines for Nasal and Pulmonary Drug Delivery
Biologics are a rapidly emerging class of therapeutics that have succeeded clinically and commercially due to their specificity and efficacy against...
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Bioprinting for Therapeutics
The pharmaceutical sector is fueled by novel, high-value products that result from research and development. We can all agree that the pharmaceutical...
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Polymer for Biomedical Applications
The structure of a polymer depends entirely on its monomer. Polymers are broadly classified into two main groups, natural and synthetic, depending on...
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Current State and Opportunities with Long-acting Injectables: Industry Perspectives from the Innovation and Quality Consortium “Long-Acting Injectables” Working Group
Long-acting injectable (LAI) formulations can provide several advantages over the more traditional oral formulation as drug product opportunities....
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Biomedical Applications of Biodegradable Polymers in Wound Care
According to the World Health Organization, it is estimated that 180,000 deaths occur annually due to burns. In the United States, it is expected...
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Bacterial Polysaccharides Versatile Medical Uses
During the last years, a lot of research results have been published concerning to new approaches to extend the use of microbial and particularly...
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Nerve Regeneration
Nerve injuries may result in neurological dysfunction or even permanent disability, which poses various challenges to physicians. In the peripheral...
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Innovative Drug Delivery Systems for Drug-Resistant Breast Cancer
Breast cancer is the most common and one of the deadliest cancers affecting women worldwide. The mainstay treatment for breast cancer is surgery and...
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Therapeutic Potential of Nanocarrier-Mediated Delivery of Phytoconstituents for Wound Healing: Their Current Status and Future Perspective
The treatment of wounds is a serious problem all over the world and imposes a huge financial burden on each and every nation. For a long time,...
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The Role of Hyaluronic Acid in Tissue Engineering
Hyaluronic acid (HA) is a glycosaminoglycan that is found in extracellular tissue in many parts of the body. It is a material of increasing...
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Quality by Design in Pharmaceutical Product and Process Development
Chapter 1 provided an overview of the QbD strategy, including its goals and main elements as well as its relation to the lifecycle approach. This...