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Analysis of normal lung irradiation in radiosurgery treatments: a comparison of lung optimized treatment (LOT) on cyberknife, 4D target volume on helical tomotherapy, and DIBH on linear accelerator
Quantitative retrospective analysis of the normal lung irradiation due to the variations of the ITV volume based on the techniques used for upper...
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Single isocenter stereotactic radiosurgery for patients with multiple brain metastases: dosimetric comparison of VMAT and a dedicated DCAT planning tool
BackgroundIn this dosimetric study, a dedicated planning tool for single isocenter stereotactic radiosurgery for multiple brain metastases using...
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Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer
BackgroundHypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic...
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Comparison of global and local gamma evaluation results using isodose levels
The aim of this study is to evaluate the behaviour of global and local gamma analyses with isodose levels. Global and local gamma evaluation were...
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Investigation of Dose Thresholds and Normalization Methods Effect on Gamma Index Analysis for SRT and SBRT Patients with a Monte Carlo Secondary Dose Check Software
PurposeWe aimed to analyze the effects of different dose thresholds (DTHs) and normalization methods on 3-dimensional (3D) gamma index analysis (GIA)...
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Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases
BackgroundThe present study identified survival and progression-free rates and evaluated prognostic factors for IVB stage cervical cancer in patients...
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Dosimetric parameters and absolute monocyte count can predict the prognosis of acute hematologic toxicity in cervical cancer patients undergoing concurrent chemotherapy and volumetric-modulated arc therapy
PurposeTo explore clinical and dosimetric predictors of acute hematologic toxicity (HT) in cervical cancer patients treated with concurrent...
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Injection of hydrogel spacer increased maximal intrafractional prostate motion in anterior and superior directions during volumetric modulated arc therapy-stereotactic body radiation therapy for prostate cancer
BackgroundThe aim of this study was to clarify the association between intrafractional prostate shift and hydrogel spacer.
MethodsThirty-eight...
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Determining tolerance levels for quality assurance of 3D printed bolus for modulated arc radiotherapy of the nose
Given the existing literature on the subject, there is obviously a need for specific advice on quality assurance (QA) tolerances for departments...
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Components of the sympathetic nervous system as targets to modulate inflammation – rheumatoid arthritis synovial fibroblasts as neuron-like cells?
BackgroundCatecholamines are major neurotransmitters of the sympathetic nervous system (SNS) and they are of pivotal importance in regulating...
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Evaluation of a highly refined prediction model in knowledge-based volumetric modulated arc therapy planning for cervical cancer
Background and purposeTo explore whether a highly refined dose volume histograms (DVH) prediction model can improve the accuracy and reliability of...
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Treatment results for patients with squamous-cell carcinoma of the anus, a single institution retrospective analysis
Background and purposeTo gain insight into the treatment outcomes for anal cancer a retrospective analysis was performed with a special emphasis on...
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MPTP Neurotoxicity: Actions, Mechanisms, and Animal Modeling of Parkinson’s Disease
The study of neurotoxicity induced by MPTP led to drastically change the perspective on Parkinson’s disease. In fact, the selective neurotoxicity...
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MLC parameters from static fields to VMAT plans: an evaluation in a RT-dedicated MC environment (PRIMO)
BackgroundPRIMO is a graphical environment based on PENELOPE Monte Carlo (MC) simulation of radiotherapy beams able to compute dose distribution in...
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Mechanisms of Dopamine Oxidation and Parkinson’s Disease
Dopamine’s ability to oxidize to aminochrome explains why this molecule may be a neurotoxic compound that induces toxicity in both cell lines and...
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Mechanisms of Dopamine Oxidation and Parkinson’s Disease
Dopamine’s ability to oxidize to aminochrome explains why this molecule may be a neurotoxic compound that induces toxicity in both cell lines and...
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Innovations in radiotherapy and advances in immunotherapy for the treatment of brain metastases
Radiotherapy for brain metastases has evolved tremendously over the past four decades, allowing for improved intracranial control of disease with...
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Evaluation of a new foetal shielding device for pregnant brain tumour patients
BackgroundThe present study aimed to propose a new foetal shielding device for pregnant cancer patients to reduce the foetal dose associated with...
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Modern Radiation Therapy Techniques and their Toxicities for Breast Cancer
Breast cancer (BC) is the major cause of death in women worldwide. It is a global issue with nearly 2.3 million patients diagnosed with BC and 0.685...
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Cochlea sparing optimized radiotherapy for nasopharyngeal carcinoma
BackgroundDefinitive chemoradiotherapy (CRT) is standard of care for nasopharyngeal carcinoma. Due to the tumor localization and concomitant...
