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1. Nanoparticle-Mediated Cancer Chemotherapy

   There are certain limitations of cancer chemotherapy including lack of specificity for tumour, drug resistance, limited aqueous solubility, short...

   Mohsin Khan in Personalized and Precision Nanomedicine for Cancer Treatment

   Chapter 2024
   

2. Target Organ Toxicity

   Several target organs such as liver, kidney, lungs, heart, ocular and visual apparatus, skin, reproductive organ, immune system, endocrine systems,...

   P K Gupta in Problem Solving Questions in Toxicology:

   Chapter 2020
   

3. Reversal of genetic brain iron accumulation by N,N′-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice

   N,N’- bis(2-mercaptoethyl)isophthalamide (NBMI) is a novel lipophilic metal chelator and antioxidant used in mercury poisoning. Recent studies have...

   Ruiying Cheng, Rajitha Gadde, ... Jonghan Kim in Archives of Toxicology

   Article 21 April 2022
   

4. Organ and Non-organ-Directed Nanotoxicity

   Humans are exposed to various nanoscale materials since childhood, and as such have become a threat to human life. Because of their small size,...

   P K Gupta in Nanotoxicology in Nanobiomedicine

   Chapter 2023
   

5. Inclusion Complexes of Daidzein with Cyclodextrin-Based Metal–Organic Framework-1 Enhance Its Solubility and Antioxidant Capacity

   Daidzein, an aglycone-type isoflavone, is useful in the prevention of atherosclerotic cardiovascular diseases. However, the solubility of daidzein...

   Yutaka Inoue, Masaaki Yoshida, ... Toshio Oguchi in AAPS PharmSciTech

   Article 18 November 2021
   

6. Use of Histology in Nutrition

   Chronic exposure to arsenic from groundwater is one of the major health concerns in several regions around the world. Binding of arsenicals with...

   Roobee Garla in Biomarkers in Nutrition

   Living reference work entry 2022
   

7. The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method

   Background

   Inhalation of multi-walled carbon nanotubes (MWCNTs) poses a potential risk to human health. In order to safeguard workers and consumers,...

   Alexia J. Taylor-Just, Mark D. Ihrie, ... James C. Bonner in Particle and Fibre Toxicology

   Article Open access 26 November 2020
   

8. Use of Histology in Nutrition

   Chronic exposure to arsenic from groundwater is one of the major health concerns in several regions around the world. Binding of arsenicals with...

   Roobee Garla in Biomarkers in Nutrition

   Reference work entry 2022
   

9. Anthelmintic activity of biosynthesized zinc oxide nanoparticles using Typha domingensis pers. against Echinococcus granulosus protoscoleces

   Background

   Over the past decade, the green synthesis of metal and metal oxide nanoparticles has attracted significant attention due to their...

   Bushra H. Shnawa, Parwin J. Jalil, ... Mukhtar H. Ahmed in Toxicology and Environmental Health Sciences

   Article 27 September 2023
   

10. Coumarin Xanthene Combined Probe for the Multi-Color Detection of Metal Ions and Electrospun Fibers Developed for Real-Time Monitoring

    A coumarin-rhodamine (RhBC)-fused colorimetric/fluorescent probe was designed and synthesized. The probe is effective in Cu ²⁺ /Hg ²⁺ ion sensing. With...

    Subbiah Ramesh, Sudalaiyandi Kumaresan in Journal of Fluorescence

    Article 09 February 2023
    

11. Nanomaterials Toxicology: An Overview

    Nanoparticles (NPs) have a wide range of applications in our daily life, such as in cosmetics, food packaging, drug delivery systems, therapeutics,...

    Sharda Gurram, Durgesh K. Jha, ... Chandrakantsing V. Pardeshi in Nanomaterial-Based Drug Delivery Systems

    Chapter 2023
    

12. Oxidative Stress and Metals in Alzheimer’s Disease

    Alzheimer’s disease (AD) is one of the progressive neurodegenerative disorders allied with genetic, lifestyle, and environmental factors and mainly...

    Shaik Ayesha Fathima, Ranika Maurya, Saba Naqvi in Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease

    Chapter 2023
    

13. Caenorhabditis elegans: Evaluation of Nanoparticle Toxicity

    The relevance of Caenorhabditis elegans (C. elegans) as an in vivo model organism in the study of nanoparticle/biological interactions and...

    Sandeep Kumar, Kitlangki Suchiang in Model Organisms to Study Biological Activities and Toxicity of Nanoparticles

    Chapter 2020
    

14. MXene Nanomaterial for Medical Application

    Biomaterials technology has advanced significantly in recent years and 2-D nanostructures have played a key role in this advancement. A new ceramic...

    Anand Salvi, Neetu Dhanda, ... Atul Thakur in Integrated Nanomaterials and their Applications

    Chapter 2023
    

15. Pharmacogenomics of Cisplatin-Induced Toxicity in Children

    Cisplatin is a widely used chemotherapeutics agent used to treat cancers in all age groups. It induces apoptosis but is deactivated by some proteins...

    Aadil Rasheed, Maliha Ghaffar, Hina Salahuddin in 'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

    Chapter 2020
    

16. Therapeutic Applications of Noble Metal (Au, Ag, Pt)-Based Nanomedicines for Melanoma

    Melanoma is considered to be the most aggressive form of skin cancer. It mostly occurs as a result of exposure to the ultra violet (UV) radiation...

    Arpita Roy, Papia Basuthakur, Chitta Ranjan Patra in Nanomedicine for Cancer Diagnosis and Therapy

    Chapter 2021
    

17. Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes

    Background

    The increasing use of metal nanoparticles in industry and biomedicine raises the risk for unintentional exposure. The ability of metal...

    Jiali Yuan, Yue Zhang, ... Qunwei Zhang in Particle and Fibre Toxicology

    Article Open access 19 March 2021
    

18. Versatile Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antileishmanial Drugs

    Mortalities associated with leishmaniasis are skyrocketing at an alarming rate. Lack of vaccine for leishmaniasis treatment is making the fight...

    Patrick O. Sakyi, Richard K. Amewu, ... Samuel K. Kwofie in Natural Product Based Drug Discovery Against Human Parasites

    Chapter 2023
    

19. Ti₃C₂ (MXene), an advanced carrier system: role in photothermal, photoacoustic, enhanced drugs delivery and biological activity in cancer therapy

    In the realm of healthcare and the advancing field of medical sciences, the development of efficient drug delivery systems become an immense promise...

    Vishal Kumar Deb, Utkarsh Jain in Drug Delivery and Translational Research

    Article 07 May 2024
    

20. Leveraging Nanotechnology in Cosmeceuticals: Formulation, Characterisation, Regulatory Status and Toxicity

    The Federal Food Drug, and Cosmetic Act 2018 clearly defines the terms “drugs” and “cosmetics”. Surprisingly, “cosmeceuticals” do not find any...

    Pranav Shah, Jaimini Gandhi, ... Shweta Gupta in Nanocarriers: Drug Delivery System

    Chapter 2021