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Prophage P1: An Example of a Prophage That Is Maintained as a Plasmid
Integration of phage DNA with a bacterial chromosome is not the only form of lysogeny. There is a growing number of reports concerning prophages that... -
Phage Infection and Lysis
Viruses are differentiated from other mobile genetic elements by the encapsidation of their genomes during some stage of their life cycles. It is... -
Pre-existing Autoantibodies Neutralizing High Concentrations of Type I Interferons in Almost 10% of COVID-19 Patients Admitted to Intensive Care in Barcelona
BackgroundIt is important to predict which patients infected by SARS-CoV-2 are at higher risk of life-threatening COVID-19. Several studies suggest...
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Psoriasis in Adolescents and Adults
Psoriasis is a common chronic immune-mediated inflammatory skin disorder, affecting the skin, nails, and joints in both children and adults.... -
A systematic review to identify novel clinical characteristics of monkeypox virus infection and therapeutic and preventive strategies to combat the virus
Since May 2022, there has been a global increase in the number of Mpox virus (MPXV) cases in countries that were previously considered non-endemic....
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Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?
AbstractAedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV),...
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Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs
Respiratory viral infections reprogram pulmonary macrophages with altered anti-infectious functions. However, the potential function of virus-trained...
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Genomic and functional characterization of five novel Salmonella-targeting bacteriophages
BackgroundThe host-unrestricted, non-typhoidal Salmonella enterica serovar Enteritidis ( S. Enteritidis) and the serovar Typhimurium ( S. Typhimurium)...
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Nosocomial infections associated to COVID-19 in the intensive care unit: clinical characteristics and outcome
Bacterial and fungal co-infection has been reported in patients with COVID-19, but there is limited experience on these infections in critically ill...
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Monkeypox Outbreak 2022, from a Rare Disease to Global Health Emergence: Implications for Travellers
MonkeypoxMonkeypox (mpox), a zoonotic diseaseZoonotic disease caused by the monkeypoxMonkeypox virus (MPXV), poses a significant public health threat... -
Acalculous cholecystitis is a common extrahepatic manifestation of hepatitis E and suggests a more serious condition
BackgroundThis study aimed to understand the incidence and clinical significance of acalculous cholecystitis in patients with acute hepatitis E (HE).
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Swarm Intelligence in Cell Entry Exclusion Phenomena in Viruses and Plasmids: How to Exploit Intelligent Gene Vector Self-Scattering in Therapeutic Gene Delivery
Many naturally occurring viral and bacterial gene transfer systems present ‘superinfection interference’ phenomena, where expression of additional... -
New Treatment Solutions
Scabies is a global public health burdensome issue and one of the most common skin diseases in the world. The estimated worldwide point prevalence is... -
Assessing Biomarkers in Viral Infection
Current biomarkers to assess the risk of complications of both acute and chronic viral infection are suboptimal. Prevalent viral infections like... -
Advances and opportunities in malaria population genomics
Almost 20 years have passed since the first reference genome assemblies were published for Plasmodium falciparum , the deadliest malaria parasite, and A...
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Immunophenotype of lymphocytes and real-world outcome of COVID-19 infection in children with hematology and oncology
BackgroundPatients with immunocompromise were suspected to encounter a high risk for severe coronavirus disease 2019 (COVID-19) infection on early...
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Reverse Genetics Systems for the De Novo Rescue of Diverse Members of Paramyxoviridae
Paramyxoviruses place significant burdens on both human and wildlife health; while some paramyxoviruses are established within human populations,... -
Entry Inhibitors of Hepatitis B and D Viruses
Human hepatitis B virus (HBV) and hepatitis D virus (HDV) cause acute and chronic infections. The latter poses a serious public health threat as it... -
Clonorchiasis and Opisthorchiasis
Clonorchiasis and opisthorchiasis are helminthic diseases caused by the liver flukes Clonorchis sinensis, Opisthorchis felineus and Opisthorchis... -
Genome Variation of Endosymbiotic Wolbachia in Introduced Populations of Asian Tiger Mosquito Aedes albopictus from Krasnodar Krai
AbstractFor determining the impact of Wolbachia endosymbiont on Aedes albopictus spread to colder environments, we have studied variation in the Wolbachia...