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Sensitivity and Subgroup Analysis
Sensitivity and subgroup analysis are one of the important analyses in meta-analysis. A sensitivity analysis is a critical component of a... -
Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis
BackgroundThis study aimed to investigate the pooled diagnostic ability of circular RNA (circRNA) molecules for diabetes mellitus.
Methods ... -
The prognostic utility of preoperative neutrophil-to-lymphocyte ratio (NLR) in patients with colorectal liver metastasis: a systematic review and meta-analysis
The neutrophil-to-lymphocyte ratio is used to reflect body's inflammatory status with prognostic value in different cancers. We aimed to investigate...
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The effect of probiotics on the risk of mortality in patients with COVID-19: systematic review and meta-analysis of randomized trials
Probiotics have been hypothesized to play a beneficial role in modulating immune responses and gut microbiota in various clinical settings. This...
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Dose response relationship between breast cancer and somatotypes during childhood: a systematic review and meta-analysis
ObjectivesThis study aims to evaluate the relationship between breast cancer and somatotypes during early life by meta-analysis and give the...
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Meta-Analysis
It is hard for clinicians to remain up to date with the innumerable publications for each topic. Conflicting results (some findings are positive,... -
Prognosis stratification of cancer patients treated with immune checkpoint inhibitors through lung immune prognostic index: a meta-analysis and systematic review
BackgroundAlthough numerous studies have reported the prognostic value of the lung immune prognostic index (LIPI) in non-small cell lung cancer...
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Association of the TRIM family protein with survival outcomes and clinicopathological features in colorectal cancer: a systematic review and meta-analysis
BackgroundThe tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance...
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Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples
Frequent and widespread testing of members of the population who are asymptomatic for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is...
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Precancerous cervical lesion and associated factors among HIV-infected women in Ethiopia: systematic review and meta- analysis
BackgroundDespite several preventative and control measures Ethiopia continues to see an increase in cervical cancer. Comprehensive evidence is very...
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The effect of vitamin C on the risk of mortality in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
Background and AimsVitamin C appears to be a viable treatment option for patients with COVID-19.
MethodsWe conducted a systematic review and...
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Treatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO
BackgroundFOLFOXIRI/bevacizumab (bev) is a first-line regimen of proven activity and efficacy in metastatic colorectal cancer. The upfront exposure...
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Acceptance of human papillomavirus vaccination and parents’ willingness to vaccinate their adolescents in Ethiopia: a systematic review and meta-analysis
IntroductionDespite the global vaccination campaign to prevent HPV-related morbidity, HPV vaccination uptake remains unacceptably low in the...
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Efficacy and safety of atezolizumab plus bevacizumab treatment for advanced hepatocellular carcinoma in the real world: a single-arm meta-analysis
BackgroundAtezolizumab plus bevacizumab was approved in 2020 as a first-line treatment for advanced hepatocellular carcinoma (HCC). The purpose of...
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Performance Validity Test Failure in the Clinical Population: A Systematic Review and Meta-Analysis of Prevalence Rates
Performance validity tests (PVTs) are used to measure the validity of the obtained neuropsychological test data. However, when an individual fails a...
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Self-swabbing versus assisted swabbing for viral detection by qRT-PCR: the experience from SARS-CoV-2 based on a meta-analysis of six prospectively designed evaluations conducted in a UK setting
PurposeIn April 2020, the UK Government implemented NHS Test and Trace to provide SARS-CoV-2 quantitative reverse transcription polymerase chain...
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Efficacy of intravenous N acetylcysteine as an adjuvant therapy in the treatment of acute aluminum phosphide Poisoning: a systematic review and meta-analysis
BackgroundAluminum phosphide toxicity is a serious problem in many countries. Unfortunately, there is no specific antidote. N-acetylcysteine has been...
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Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs
BackgroundThere is an urgent need for an extensive evaluation of benzimidazole efficacy in humans. In veterinary science, benzimidazole resistance...
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Integrated analysis identifies GABRB3 as a biomarker in prostate cancer
BackgroundTreatment failure following androgen deprivation therapy (ADT) presents a significant challenge in the management of advanced prostate...