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Alcohol and the vasculature: a love-hate relationship?
Alcohol consumption is a leading risk factor and increases the risk of liver diseases, cancers, tuberculosis, and injuries. The relationship between...
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Seasonal and monthly variation in multiple sclerosis relapses: a systematic review and meta-analysis
BackgroundMultiple Sclerosis (MS) relapses are episodes of transient disease exacerbation. There are contradictory findings regarding seasonal...
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New Effect in Physiology of Human Nervous Muscle System
A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than...
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Critical Thinking Across the Sciences
The study of critical thinkingThinking, critical has become a recognized academic field because of its educational and social value. Critical...
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Heat Shock Protein HSP27 and the Status of the Glutathione System in Dexamethasone-Induced Apoptosis of Jurkat Tumor Cells
We studied the effect of the HSP27 inhibitor, 5-(5-ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)-isoxazole, at a final concentration of 0.1 μM...
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Environmental barriers perceived by the Finnish population with spinal cord injury: a cross-sectional survey
Study designCross-sectional survey of the Finnish population with spinal cord injury (SCI).
ObjectivesTo explore the frequencies of perceived...
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Evolving roles of CD38 metabolism in solid tumour microenvironment
Given that plenty of clinical findings and reviews have already explained in detail on the progression of CD38 in multiple myeloma and haematological...
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Aneuploidy during development in facultative parthenogenetic Drosophila
From concatenated chromosomes to polyploidization, large-scale genome changes are known to occur in parthenogenetic animals. Here, we report mosaic...
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Computational Model of the Mind: How to Think About Complex Systems in Nature
The collaborationCollaboration between the areas of computationComputation and the biological sciencesScience in the last two decades has changed in...
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Cancer Care Delivery Among Breast Cancer Patients: Is it the Same for All?
Among Hispanic women, breast cancer is the most common cancer accounting for close to 30% of the total cancer cases. It is estimated that in 2018...
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Antidotal treatment of botulism in rats by continuous infusion with 3,4-diaminopyridine
Botulinum neurotoxins (BoNTs) are highly potent, select agent toxins that inhibit neurotransmitter release at motor nerve terminals, causing muscle...
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Predictive biomarkers for immune-related adverse events in cancer patients treated with immune-checkpoint inhibitors
PurposeThe objective of this study was to identify potential predictors of immune-related adverse events (irAEs) in cancer patients receiving immune...
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Possible Implications of Obesity-Primed Microglia that Could Contribute to Stroke-Associated Damage
Microglia, the resident macrophages of the central nervous system, are essential players during physiological and pathological processes. Although...
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Breast cancer risk factors and mammographic density among 12518 average-risk women in rural China
BackgroundMammographic density (MD) is a strong risk factor for breast cancer. We aimed to evaluate the association between MD and breast cancer...
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Cell proliferation, drug distribution and therapeutic effects in relation to the vascular system of solid tumours
In this perspective, the authors summarise some properties of the solid tumour micro-environment that have been explored during the last 55 years. It...
