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A Novel Point-of-Care Rapid Diagnostic Test for Screening Individuals for Antibody Deficiencies
PurposeNo rapid diagnostic test exists to screen individuals for primary antibody deficiencies (PAD) at or near the point of care. In settings at...
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Acceptability and safety of thermal ablation to prevent cervical cancer in sub-Saharan Africa
BackgroundThe World Health Organization recommends thermal ablation as an alternative to cryotherapy to treat women with precancerous lesions in...
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Implementation studio: implementation support program to build the capacity of rural community health educators serving immigrant communities to implement evidence-based cancer prevention and control interventions
PurposeRural community-based organizations (CBOs) serving immigrant communities are critical settings for implementing evidence-based interventions...
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A qualitative study of infection prevention and control practices in the maternal units of two Ghanaian hospitals
IntroductionHealthcare-associated infections (HAIs) remain a common challenge in healthcare delivery, with a significant burden in low- and...
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Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence
Gene expression-based recurrence assays are strongly recommended to guide the use of chemotherapy in hormone receptor-positive, HER2-negative breast...
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Treatment outcomes of esophageal cancer in Eastern Africa: protocol of a multi-center, prospective, observational, open cohort study
BackgroundEsophageal squamous cell carcinoma (ESCC) is a major cause of cancer morbidity and mortality in Eastern Africa. The majority of patients...
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Interventions and Public Health Activities Performed by Community Pharmacists
This entry discusses and narrates interventions and public health roles performed by community pharmacists. This is done by evidence synthesis of...
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Health system barriers to the implementation of the national action plan to combat antimicrobial resistance in Vietnam: a sco** review
BackgroundVietnam is among 11 countries in the Western Pacific region that has developed a National Action Plan for Antimicrobial Resistance (NAPCA).
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A robust and parsimonious machine learning method to predict ICU admission of COVID-19 patients
AbstractIn this article, we discuss the development of prognostic machine learning (ML) models for COVID-19 progression, by focusing on the task of...
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The prevalence and clinical context of antimicrobial resistance amongst medical inpatients at a referral hospital in Rwanda: a cohort study
BackgroundAntimicrobial resistance (AMR) is a growing global concern. AMR surveillance is a crucial component of the international response;...
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Point of Care Molecular Diagnostics in Cancer
Among the major challenges facing the clinical applications of point of care (PoC) devices is to enable rapid, accurate, convenient, and...
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Implementation of the WHO core components of an infection prevention and control programme in two sub-saharan African acute health-care facilities: a mixed methods study
BackgroundThe coronavirus pandemic again highlighted the need for robust health care facility infection prevention and control (IPC) programmes. WHO...
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Evaluating cancer genetic services in a safety net system: overcoming barriers for a lasting impact beyond the CHARM research project
Underserved patients face substantial barriers to receiving cancer genetic services. The Cancer Health Assessments Reaching Many (CHARM) study...
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First field study using Strong-LAMP for diagnosis of strongyloidiasis in Cubal, Angola
BackgroundStrongyloides stercoralis infection is a common neglected tropical disease distributed worldwide, mainly in tropical and subtropical...
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Ethics of artificial intelligence in prenatal and pediatric genomic medicine
This paper examines the ethics of introducing emerging forms of artificial intelligence (AI) into prenatal and pediatric genomic medicine....
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Translating research to usual care of children with sickle cell disease in Northern Nigeria: lessons learned from the SPRING Trial Team
ObjectivesEvidence-based practice for stroke prevention in high-income countries involves screening for abnormal transcranial Doppler (TCD) velocity...
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Opening the ‘black box’ of collaborative improvement: a qualitative evaluation of a pilot intervention to improve quality of malaria surveillance data in public health centres in Uganda
BackgroundDemand for high-quality surveillance data for malaria, and other diseases, is greater than ever before. In Uganda, the primary source of...
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Scabies
Scabies is a Neglected Tropical Disease (NTD) and is endemic in many resource-poor settings, predominantly in tropical regions and under crowded...
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Development and Evaluation of an e-Learning Module for Low- and Middle-Income Countries on the Safe Handling of Chemotherapy Drugs
Despite the growing use of chemotherapy drugs in resource-constrained settings, training opportunities on safe handling practices are lacking. This...
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Experiences of healthcare personnel on the efficacy of artemisinin-based combination therapy and malaria diagnosis in hospitals in Uganda
BackgroundThe risk of widespread resistance to artemisinin-based combination therapy (ACT) remains high in Uganda following detection of Plasmodium...