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A qualitative investigation of biomedical informatics interoperability standards for genetic test reporting: benefits, challenges, and motivations from the testing laboratory’s perspective
PurposeGenetic laboratory test reports can often be of limited computational utility to the receiving clinical information systems, such as clinical...
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Pay-it-forward incentives for hepatitis virus testing in men who have sex with men: a cluster randomized trial
Pay-it-forward incentives involve having a person receive a free test with community-generated messages and then asking if those who received a free...
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Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review
Recent preclinical research exploring how neuropeptide transmitter systems regulate motivated behavior reveal the increasing importance of sex as a...
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Evaluation of approaches to recruitment of racially and ethnically diverse breast cancer patients from an integrated health care setting for collection of observational social network data
PurposeWe compared approaches to recruitment of diverse women with breast cancer in a study designed to collect complex social network data.
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Chronic Standard Scheduled-Diet Improves Memory Performance and Is Associated with Positive Correlation between Plasma Ghrelin and Hippocampal Dopamine Level in Rats
AbstractDietary content/habit is known to play a prominent role in memory function, in part via a direct effect of ghrelin on the hippocampus. Given...
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Transgenerational Susceptibility to Food Addiction-Like Behavior in Rats Associates to a Decrease of the Anti-Inflammatory IL-10 in Plasma
Maternal nutritional programming by energy-dense foods leads to the transgenerational heritance of addiction-like behavior. Exposure to energy-dense...
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Spatial Distribution of Neurons Expressing Single, Double, and Triple Molecular Characteristics of Glutamatergic, Dopaminergic, or GABAergic Neurons in the Mouse Ventral Tegmental Area
The ventral tegmental area (VTA) is a heterogeneous midbrain area that plays a significant role in diverse neural processes such as reward, aversion,...
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Attentional capacities prior to drug exposure predict motivation to self-administer nicotine
RationaleNicotine can enhance attention and attribution of incentive salience to nicotine-associated stimuli. However, it is not clear whether...
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Poor inhibitory control predicts sex-specific vulnerability to nicotine rewarding properties in mice
RationaleThe risk of becoming addicted to tobacco varies greatly from individual to individual, raising the possibility of behavioural biomarkers...
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Consensus Paper: Cerebellum and Reward
Cerebellum is a key-structure for the modulation of motor, cognitive, social and affective functions, contributing to automatic behaviours through...
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Acute food deprivation-induced relapse to heroin seeking after short and long punishment-imposed abstinence in male rats
RationalStress is a major trigger for drug relapse in humans and animal models, even after prolonged abstinence. However, animal models for...
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Evaluating a community engagement model for malaria elimination in Haiti: lessons from the community health council project (2019–2021)
BackgroundCommunity engagement (CE) plays a critical role in malaria control and elimination. CE approaches vary substantially, with more...
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Efficiency of structural connectivity networks relates to intrinsic motivation in children born extremely preterm
Intrinsic motivation is essential for academic success and cognitive growth, but limited work has examined the neuroanatomical underpinnings of...
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Behavioural determinants of malaria risk, prevention, and care-seeking behaviours among forest-goers in Cambodia
BackgroundCambodia has made significant progress towards achieving malaria elimination by 2025. Cases continue to decrease and are primarily...
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5-HT2C receptor perturbation has bidirectional influence over instrumental vigour and restraint
The serotonin (5-HT) system , particularly the 5-HT 2C receptor, has consistently been implicated in behavioural control. However, while some studies...
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The reproducibility debate is an opportunity, not a crisis
There are many factors that contribute to the reproducibility and replicability of scientific research. There is a need to understand the research...
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Relationship between opioid cross-tolerance during buprenorphine stabilization and return to opioid use during buprenorphine dose tapering
RationaleOpioid injection drug use (IDU) has been linked to a more severe pattern of use (e.g. tolerance, overdose risk) and shorter retention in...
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Behaviour Change Techniques in Computerized Cognitive Training for Cognitively Healthy Older Adults: A Systematic Review
We aimed to describe behaviour change techniques (BCT) used in trials evaluating computerised cognitive training (CCT) in cognitively healthy older...
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Are medication effects on subjective response to alcohol and cue-induced craving associated? A meta regression study
RationaleAlcohol administration and cue-reactivity paradigms are frequently used to screen for the initial efficacy of medications for alcohol use...