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Molecular characterization of human astrovirus infection in children under 5 years of age with acute gastroenteritis in Tehran, Iran, 2021–2022: co-infection with rotavirus
Human astroviruses (HAstVs) are considered important causative pathogens of acute gastroenteritis (AGE) in children under 5 years of age worldwide,...
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Human adenovirus binding to host cell receptors: a structural view
Human Adenoviruses (HAdVs) are a family of clinically and therapeutically relevant viruses. A precise understanding of their host cell attachment and...
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Assessing the Response of Human NK Cell Subsets to Infection by Clinically Isolated Virus Strains
Natural killer (NK) cells play a critical role in defending against virus infections. Investigating human NK cell antiviral functions is of prime... -
Comparative analysis of clinical features of SARS-CoV-2 and adenovirus infection among children
BackgroundThe new emerging coronavirus disease 2019 (COVID-19) overall shares similar symptoms with other common respiratory viral infections. We...
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Whole genomic analysis of a potential recombinant human adenovirus type 1 in Qinghai plateau, China
Human adenoviruses (HAdVs) are prevalent in patients with respiratory infections, in which recombination has important implications for viral...
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Seroprevalence of Neutralizing Antibodies against Six Human Adenovirus Types Indicates the Low Level of Herd Immunity in Young Children from Guangzhou, China
Human adenoviruses (HAdVs) commonly cause many diseases such as respiratory diseases, gastroenteritis, cystitis worldwide. HAdV-3, -7, -4 and...
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Genetic diversity of human adenovirus and human astrovirus in children with acute gastroenteritis in Northwest Ethiopia
Human adenovirus (HAdV) and human astrovirus (HAstV) are common causes of gastroenteritis. Data on the prevalence and diversity of enteric viruses...
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First evidence of a new simian adenovirus clustering with Human mastadenovirus F viruses
BackgroundAdenoviruses play an important role as human pathogens, though most infections are believed to be asymptomatic. The over 100 human...
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Quantitative Detection of Human Adenovirus and Human Rotavirus Group A in Wastewater and El-Rahawy Drainage Canal Influencing River Nile in the North of Giza, Egypt
Environmental monitoring is critical in a develo** country like Egypt where there is an insufficient framework for recording and tracking...
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Detection of Parvovirus B19 genome in human heart tissue samples
ObjectiveIdentifying viral genomes in human heart tissues is critical for disease diagnosis and assessment of cardiovascular damage. Human heart...
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Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells
Glioblastoma multiforme (GBM) is the most common malignant primary brain cancer affecting the adult population. Median overall survival for GBM...
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Molecular and epidemiological characterization of human adenoviruses infection among children with acute diarrhea in Shandong Province, China
BackgroundHuman adenovirus (HAdV) had been recognized as one of the most common enteric viruses associated with acute diarrhea in children. The...
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Detection of human adenoviruses in influenza-negative patients with respiratory tract infections in Nanning, China
BackgroundHuman adenoviruses (HAdV) have been known to cause a range of diseases, including respiratory tract infections (RTIs). However, there is...
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Adenovirus delivery of encoded monoclonal antibody protects against different types of influenza virus infection
Due to the high mutation and recombination rates of the influenza virus, current clinically licensed influenza vaccines and anti-influenza drugs...
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Epidemiology and clinical severity of the serotypes of human parainfluenza virus in children with acute respiratory infection
BackgroundAcute respiratory infections (ARI) are a threat to human health and survival, resulting in many paediatric hospitalisations. However, the...
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Understanding and addressing barriers to successful adenovirus-based virotherapy for ovarian cancer
Ovarian cancer is the leading cause of death among women with gynecological cancer, with an overall 5-year survival rate below 50% due to a lack of...
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Coxsackievirus and Adenovirus Receptor (CXADR): Recent Findings and Its Role and Regulation in Spermatogenesis
Coxsackievirus and adenovirus receptor (CXADR) belongs to immunoglobulin superfamily of cell adhesion molecules. It expresses in most tissues, but... -
Adenovirus vector-mediated YKL-40 shRNA attenuates eosinophil airway inflammation in a murine asthmatic model
Recent studies have revealed that YKL-40 is involved in the pathogenesis of asthma. However, its specific mechanism remains unclear. The present...