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The effects of host quantitative genetic architecture on the gut microbiota composition of Chinook salmon (Oncorhynchus tshawytscha)
The microbiota consists of microbes living in or on an organism and has been implicated in host health and function. Environmental and host-related...
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Geography, not lifestyle, explains the population structure of free-living and host-associated deep-sea hydrothermal vent snail symbionts
BackgroundMarine symbioses are predominantly established through horizontal acquisition of microbial symbionts from the environment. However, genetic...
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Host Immune Gene Polymorphism and Cancer
The immune system keeps the host body safe and protected from diseases. Genetic diseases can often manipulate the immune genes at genetic levels so...
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CHIKV strains Brazil (wt) and Ross (lab-adapted) differ with regard to cell host range and antiviral sensitivity and show CPE in human glioblastoma cell lines U138 and U251
Chikungunya virus (CHIKV), a (re)emerging arbovirus, is the causative agent of chikungunya fever. To date, no approved vaccine or specific antiviral...
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Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host
BackgroundExtracellular vesicles (EVs) are membranous structures that are formed during pathophysiology, host-parasite interactions and parasite...
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Computational network analysis of host genetic risk variants of severe COVID-19
BackgroundGenome-wide association studies have identified numerous human host genetic risk variants that play a substantial role in the host immune...
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Deciphering the host genetic factors conferring susceptibility to severe COVID-19 using exome sequencing
The COVID-19 pandemic remains a significant public health concern despite the new vaccines and therapeutics. The clinical course of acute SARS-CoV-2...
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The oviposition cue indole inhibits animal host attraction in Aedes aegypti (Diptera: Culicidae) mosquitoes
BackgroundMosquitoes are responsible for disease transmission worldwide. They possess the ability to discriminate between different ecological...
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Systems genetics identifies miRNA-mediated regulation of host response in COVID-19
BackgroundIndividuals infected with SARS-CoV-2 vary greatly in their disease severity, ranging from asymptomatic infection to severe disease. The...
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Lung microbial-host interface through the lens of multi-omics
In recent years, our understanding of the microbial world within us has been revolutionized by the use of culture-independent techniques. The use of...
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Gill-associated bacteria are homogeneously selected in amphibious mangrove crabs to sustain host intertidal adaptation
BackgroundThe transition from water to air is a key event in the evolution of many marine organisms to access new food sources, escape water hypoxia,...
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Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution
BackgroundSchistosomiasis is a neglected tropical disease that afflicts millions of people worldwide; it is caused by Schistosoma, the only dioecious...
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Effects of host species on microbiota composition in Phlebotomus and Lutzomyia sand flies
BackgroundBlood-sucking phlebotomine sand flies are vectors of the protozoan parasites Leishmania spp. Although the intestinal microbiota is...
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Host Immune Response to Scabies
Scabies infection is associated with heightened total IgE immunoglobulin and IgE antibodies to scabies antigens, with both being extremely high for...
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Overcoming Biopharmaceutical Interferents for Quantitation of Host Cell DNA Using an Automated, High-Throughput Methodology
The rapid development of biologics and vaccines in response to the current pandemic has highlighted the need for robust platform assays to...
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Species richness of bat flies and their associations with host bats in a subtropical East Asian region
BackgroundUnderstanding the interactions between bat flies and host bats offer us fundamental insights into the coevolutionary and ecological...
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Whipworm secretions and their roles in host-parasite interactions
Whipworm (Trichuris) is a genus of roundworms that causes gastrointestinal infections in humans and animals. Of particular interest are T. trichiura, ...
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Giardia VSPAS7 protein attenuates Giardia intestinalis-induced host macrophage pyroptosis
BackgroundThe unicellular protozoan parasite Giardia intestinalis , which primarily infects humans and animals such as cattle and sheep, is having a...
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Using the collaborative cross to identify the role of host genetics in defining the murine gut microbiome
BackgroundThe human gut microbiota is a complex community comprised of trillions of bacteria and is critical for the digestion and absorption of...
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Timing matters: age-dependent impacts of the social environment and host selection on the avian gut microbiota
BackgroundThe establishment of the gut microbiota in early life is a critical process that influences the development and fitness of vertebrates....
