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Prevailing of HPV-16 and 52 genotype in 2022–2023 in Sanandaj, Iran
IntroductionHuman papillomavirus (HPV) presents a potential threat to the onset of carcinogenesis in the cervix, anogenital regions, and oropharynx....
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The contribution of genotype-guided selection of P2Y12 inhibitor on prognosis in ACS /CCS patients undergoing percutaneous coronary intervention: a retrospective cohort study
PurposeWe aimed to explore the contribution of genotype-guided selection of P2Y 12 inhibitors on prognosis in Chinese patients with acute coronary...
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Scalable bias-corrected linkage disequilibrium estimation under genotype uncertainty
Linkage disequilibrium (LD) estimates are often calculated genome-wide for use in many tasks, such as SNP pruning and LD decay estimation. However,...
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Current Management of Patients with HCV Genotype 2
Treatment landscape for virus hepatitis C (HCV) has continuously evolved in the last 5 years. The current standard of care is a pangenotypic... -
Male and female genotype and a genotype-by-genotype interaction mediate the effects of mating on cellular but not humoral immunity in female decorated crickets
Sexually antagonistic coevolution is predicted to lead to the divergence of male and female genotypes related to the effects of substances...
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Bone mineral density in high-level endurance runners: Part B—genotype-dependent characteristics
PurposeInter-individual variability in bone mineral density (BMD) exists within and between endurance runners and non-athletes, probably in part due...
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A combinatorial genetic strategy for exploring complex genotype–phenotype associations in cancer
Available genetically defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer....
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Fast and accurate population admixture inference from genotype data from a few microsatellites to millions of SNPs
Model-based (likelihood and Bayesian) and non-model-based (PCA and K -means clustering) methods were developed to identify populations and assign...
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Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb
Focal cortical dysplasia type II (FCDII) is the most common cause of drug-resistant focal epilepsy in children. Herein, we performed a deep...
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Serotonin Transporter (SLC6A4) and FK506-Binding Protein 5 (FKBP5) Genotype and Methylation Relationships with Response to Meditation in Veterans with PTSD
Meditation-based interventions are novel and effective non-pharmacologic treatments for veterans with PTSD. We examined relationships between...
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Full genotype characterization of Brazilian canine G3P[3] strains during a 10-year survey (2012–2021) of rotavirus infection in domestic dogs and cats
There is a dearth of information on the molecular epidemiology of rotaviruses in pets in Brazil. The aim of this study was to monitor rotavirus...
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Genotypic characterization of Japanese encephalitis virus circulating in swine population of India: Genotype-III still in dominance
Swine is considered as a suitable sentinel to predict Japanese encephalitis virus (JEV) outbreaks in humans. The present study was undertaken to...
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Participant perspective on the recall-by-genotype research approach: a mixed-method embedded study with participants of the CHRIS study
Recall-by-genotype (RbG) research recruits participants previously involved in genetic research based on their genotype. RbG enables the further...
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Longitudinal Genotype-Phenotype (Vineland Questionnaire) Characterization of 15 ADNP Syndrome Cases Highlights Mutated Protein Length and Structural Characteristics Correlation with Communicative Abilities Accentuated in Males
Activity-dependent neuroprotective protein (ADNP) is essential for neurodevelopment and de novo mutations in ADNP cause the ADNP syndrome. From brain...
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The prevalence and genotype distribution of high-risk human papillomaviruses among women in **anning, China
BackgroundThe persistent infection of high-risk Human papillomavirus(HPV) is considered the main cause of cervical intraepithelial neoplasia and...
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First report of Ikeda genotype of Theileria orientalis in Mithun (Bos frontalis) from northeastern hilly region of India
Oriental theileriosis caused by Theileria orientalis , previously considered a benign disease, is posing a significant threat to the livestock...
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Establishment of reverse genetics for genotype VII Newcastle disease virus and altering the cell tropism by inserting TMPRSS2 into the viral genome
Newcastle disease (ND) is the most important infectious disease in poultry, which is caused by avian orthoavulavirus type 1 (AOAV-1), previously...
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Dengue virus 3 genotype I (GI) lineage 1 (L1) isolates elicit differential cytopathic effect with syncytium formation in human glioblastoma cells (U251)
BackgroundDengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further...
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Human papillomavirus prevalence and genotype distribution landscapes in Shannan City, Tibet Tibetan Autonomous Region, China
BackgroundData regarding human papillomavirus (HPV) prevalence and genotype distribution are limited in Shannan City, Tibet Tibetan Autonomous...