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Pyridine-2,6-Dicarboxylic Acid As a Facile and Highly Selective “Turn-Off” Fluorimetric Chemosensor for Detection of Cu (II) Ions in Aqueous Media
Copper metal is third most abundant trace element in human body. Determination of Cu (II) ions is a burning topic in field of environment protection...
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Immunoassay and Mass Spectrometry Methods for Tau Protein Quantification in the Cerebrospinal Fluid
Quantification of tau proteins in the cerebrospinal fluid is a major biomarker for the positive diagnosis of Alzheimer’s disease, as well as for...
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Fluorescence Enhancement Based Quantification of Human Serum Albumin from Biological Sample Using Indole Based Nanosuspension: Molecular Interactions and Molecular Docking Studies
Fluorescent 3-[(E)-(2-phenylhydrazinylidene) methyl]-1H-indole (PHI) was synthesized by condensation of indole-3-carboxaldehyde and phenyl hydrazine...
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Characterization and Quantification of the Fatty Acid Amidome
Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, we detail the methods we have used to identify,...
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A Simple Method for Visual Assessment and Quantification of Altered Subcellular Localization of Nuclear Receptors
All nuclear receptors reside in the nuclear compartment when transcriptionally active. However, their subcellular localization can vary when...
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Quantification of Neuroinflammatory Markers in Blood, Cerebrospinal Fluid, and Resected Brain Samples Obtained from Patients
Cytokines have the potential to be the ideal biomarkers to track the onset and progression of immune-mediated diseases, study the development of...
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Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer
BackgroundPelvic magnetic resonance imaging (MRI) and whole-body positron emission tomography-computed tomography (PET-CT) play an important role at...
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Age induced interactions between heart rate variability and systolic blood pressure variability using approximate entropy and recurrence quantification analysis: a multiscale cross correlation analysis
The purpose of this study is to study the effect of age on the correlation between heart rate variability (HRV) and blood pressure variability (BPV)....
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[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data
ObjectivesReactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study...
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Dynamic intervention to enhance the stability of PEGylated Ibrutinib loaded lipidic nano-vesicular systems: transitioning from colloidal dispersion to lyophilized product
Liposomes being a promising colloidal system facilitates delivery of drugs with limited pharmacokinetic properties to achieve desirable clinical...
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An emergent neural coactivity code for dynamic memory
Neural correlates of external variables provide potential internal codes that guide an animal’s behavior. Notably, first-order features of neural...
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Combined in Silico Prediction Methods, Molecular Dynamic Simulation, and Molecular Docking of FOXG1 Missense Mutations: Effect on FoxG1 Structure and Its Interactions with DNA and Bmi-1 Protein
FoxG1 encoded by FOXG1 gene is a transcriptional factor interacting with the DNA of targeted genes as well as with several proteins to regulate the...
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Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis
A great bulk of recent experimental evidence suggests the key role of the complex crosstalk between the extracellular matrix (ECM) and the cellular...
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Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment
BackgroundHuman papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify...
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Determination of Lead in Bee Products by Solid Surface Fluorescence Using Complexation and Coacervation at Room Temperature Processes. An Environmental Friendly Methodology
An accurate, economic and green methodology for Pb(II) monitoring in bee products is proposed. Complexed metal traces were preconcentrated on Nylon...
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Tissue Imaging and Quantification Relying on Endogenous Contrast
Cell-matrix interactions play an important role in regulating a variety of essential processes in multicellular organisms, and are closely associated...
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Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA
BackgroundBlood plasma, one of the most studied liquid biopsies, contains various molecules that have biomarker potential for cancer detection,...
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Gyrolab Immunoassays: Miniaturization, Automation, and Integration into a Rapid Workflow
Gyrolab® is an open immunoassay platform that automates the complete immunoassay protocol in a microfluidic disc. The column profiles generated with...
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Develo** an Analytical Method Based on Graphene Quantum Dots for Quantification of Deferiprone in Plasma
In the world of nanotechnology, graphene quantum dots (GQDs) have been considerably employed in numerous optical sensing and bioanalytical...
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Bimanual finger coordination in professional and amateur darbuka players
Professional hand percussionists who play the darbuka (a drum from the Middle East) show fast and stable bimanual finger coordination compared to...
