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Showing 81-100 of 149 results
  1. Physiological Functions of the Liver

    The liver has a strategically important position in the circulation. It is the first organ that comes in contact with the blood after its exposure to...
    D. Häussinger in Comprehensive Human Physiology
    Chapter 1996
  2. Subcellular Biochemical and Pathological Correlates in Experimental Models of Hepatotoxicity

    Side effects of drugs often result from impairment of liver function or structural damage to hepatocytes. To evaluate toxic interactions, the...
    G. Feuee, F. A. Iglesia in Drug-Induced Hepatotoxicity
    Chapter 1996
  3. Hepatotoxicity of Cardiovascular Drugs

    Society often pays a price for the progress achieved in the therapeutic benefits offered by new drugs, namely, an increased incidence of toxic side...
    R. G. Cameron, F. A. de la Iglesia, G. Feuer in Drug-Induced Hepatotoxicity
    Chapter 1996
  4. Localization of Alagille syndrome to 20p11.2-p12 by linkage analysis of a three-generation family

    Alagille syndrome (AGS) or arteriohepatic dysplasia is a rare but well-defined clinical entity that is usually inherited as an autosomal dominant...

    F. A. Hol, B. C. J. Hamel, ... E. C. M. Mariman in Human Genetics
    Article 01 June 1995
  5. Stem Cell Activation in the Acetylaminofluorene-Treated Regenerating Rat Liver: A Bile Ductular Reaction?

    The ability of the liver to regenerate in response to the loss of hepatocytes is widely recognised, and this is usually accomplished by the...
    T. V. Anilkumar, Matthew Golding, ... Malcolm Alison in Liver Carcinogenesis
    Conference paper 1994
  6. The immunosuppressant FK506 inhibits the damage to mouse pancreatic islets induced by low dose streptozocin

    Diabetes mellitus was induced in 40 male C57BL6 mice by injection of a low dose of streptozocin (45 mg/kg body weight) on 5 consecutive days. Twenty...

    Gianpaolo Papaccio, Michael Latronico, Gabriella Chieffi Baccari in Cell and Tissue Research
    Article 01 September 1994
  7. The Uridine Diphosphate Glucuronosyltransferase Multigene Family: Function and Regulation

    Glucuronidation is a major detoxication pathway in all vertebrates examined, from the most primitive (fish; Clarke et al. 1991) to the most evolved...
    Chapter 1994
  8. Roles of Uridine Diphosphate Glucuronosyltransferases in Chemical Carcinogenesis

    Roles of isozymes of the uridine diphosphate (UDP)-glueuronosyltransferase (UGT) family (EC 2.4.1.17) will be discussed in the light of recent...
    Chapter 1994
  9. Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9

    In the human paired box-containing ( PAX ) gene family, only two members, PAX-3 and PAX-6 , which are associated with Waardenburg's syndrome and...

    Paula Stapleton, Andreas Weith, ... Meinrad Busslinger in Nature Genetics
    Article 01 April 1993
  10. Significance of the peri-insular extracellular matrix for islet isolation from the pancreas of rat, dog, pig, and man

    The presence and distribution in the peri-insular region of extracellular matrix, and in particular basement membrane, was investigated in a...

    J. H. M. van Deijnen, C. E. Hulstaert, ... R. van Schilfgaarde in Cell and Tissue Research
    Article 01 January 1992
  11. Differential expression of translation-associated genes in benign and malignant human breast tumours

    The human gene sequences encoding the translation-associated functions of alpha-subunit of elongation factor 1 (EF-1 alpha) and the ubiquitin...

    SM Adams, MGF Sharp, ... JM Varley in British Journal of Cancer
    Article 01 January 1992
  12. Natural Toxicants in Foods

    The purpose of exploring the potential naturally occurring toxic hazards of food plants is not to suggest an irrational avoidance of these common...
    Ross C. Beier, Herbert N. Nigg in Phytochemical Resources for Medicine and Agriculture
    Chapter 1992
  13. Synaptophysin immunoreactivity in the mammalian endocrine pancreas

    Synaptophysin, a major membrane glycoprotein of small presynaptic vesicles in neurons, has also been found in microvesicles of endocrine cells, e.g.,...

    P. Redecker, A. Jörns, ... D. Grube in Cell and Tissue Research
    Article 01 June 1991
  14. Cellular and Molecular Mechanisms of Hepatocarcinogenesis Associated with Hepadnavirus Infection

    A large number of inorganic and organic chemicals act as carcinogens in the liver. Most of these are not active until they are metabolized into...
    C. E. Rogler in Hepadnaviruses
    Chapter 1991
  15. The antigen of bile canaliculi of the mouse hepatocyte: identification and ultrastructural localization

    The AgB10 antigen of bile canaliculi of the mouse hepatocyte was identified using monoclonal antibodies. The M r value of 116000 for AgB10 was...

    N. I. Kuprina, V. N. Baranov, ... A. I. Goussev in Histochemistry
    Article 01 June 1990
  16. N-Nitroso Compounds

    The N-nitroso compounds fall into the category of carcinogens discovered through proposed industrial use (Barnes 1974). In the early 1950s the then...
    Chapter 1990
  17. Immunocytochemical evidence of phospholipase A2 in pancreatic tumors — Diagnostic values

    Phospholipase A 2 is an enzyme which is produced in acinar cells, and persists even in regressive states of chronic pancreatitis, when the production...

    P. Stömmer in Klinische Wochenschrift
    Article 01 February 1989
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