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Omic-Based Biomarkers Discovery in Alzheimer’s Disease: High-Throughput Approaches
The discovery of novel metabolomic, proteomic, lipidomic, and transcriptomic (mRNA and miRNA) biomarkers in serum, plasma, brain, and CSF is a... -
Develo** the Innovative Gene Geographical and Genomic Technologies for Identification and Revealing the Personal Features by Studying the Gene Pools of the Regional Populations
AbstractGlobal and Russian experience in using DNA technologies in investigation of crimes showed that the technologies are superior to other...
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13C-Fingerprinting and Metabolic Flux Analysis of Bacterial Metabolisms
13C-assisted metabolism analysis provides rigorous calculations of the intracellular reaction rates (i.e., fluxes) within the central metabolism of... -
STR Ty** of European Elk (Moose) and European Roe Deer with Novel Forensic Assays Reveals Contrasting Patterns of Genetic Structure of the Two Cervids in Belarus
AbstractCervids are popular game mammals and frequent victims of poaching in Europe. Investigation into illegal hunting and commercialisation often...
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Biotechnology in Medicine: Fundamentals
Biotechnology is a diverse field with important implications in everyday life. It finds its use in research, medicine, agriculture, and chemical... -
DNA Fingerprinting Techniques for Forensic Application: Past, Present, and Future
The discovery of DNA fingerprinting has revolutionized the world of forensic science and started the wave that it can be helpful in solving crime... -
Neuroanatomical Tracing Based on Selective Fluorochrome Expression in Transgenic Animals
The present chapter focuses on new developments in neuroanatomical tracing techniques. Two recent innovations are highlighted: the use of transgenic... -
Diagnostic outcome of pro bono neurogenetic diagnostic service in Sri Lanka: A wealth creation
The inherited disease community in Sri Lanka has been widely neglected. This article aimed to present accumulated knowledge in establishing a pro...
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Sexual Offences: Recent Methods of Investigation
A sexual offense is a crime of violence against a person’s body that causes physical trauma, emotional distress, and suffering of victims. The... -
Results of Camelus dromedarius and Camelus bactrianus Genoty** by Alpha-S1-Casein, Kappa-Casein Loci, and DNA Fingerprinting
Genoty** of Kazakh camels Camelus dromedarius (milk breed) ( n = 18) and Camelus bactrianus (meat breed) ( n = 18) by alpha-S 1 -casein (αs 1 -CN) and...
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Evidence and Identification
A relatively recent area of criminal investigation is wildlife forensics. Its objectives are to correlate the evidence from crime scenes to a suspect... -
Suche nach krankheitsverursachenden Genen
Von den etwa 4000 bekannten menschlichen Erbkrankheiten ist nur eine Handvoll krankheitsverursachender Gene kartiert worden. Ein Gen (mit einer... -
Vibrio cholerae
Cholera caused by toxigenic Vibrio cholerae is a major public health problem in many develo** countries, where outbreaks and sporadic infections... -
Techniques Involved in DNA Fingerprinting: Isolation, Quantification, PCR, Genoty**, and Analysis
The primary objective of forensic DNA fingerprinting is to establish the relatedness between the questioned samples and reference samples with... -
Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma
BackgroundDedifferentiated chondrosarcoma (DDCS) is an aggressive bone tumour with a poor prognosis and no effective treatment. Because changes in...
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Genetic diversity and haplotype analysis of Leishmania tropica identified in sand fly vectors of the genera Phlebotomus and Sergentomyia using next-generation sequencing technology
Next-generation sequencing (NGS) was used to investigate the genetic diversity of Leishmania tropica in the sand fly vector, targeting the internal...
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Gesamtes Genom und Next-generation-Sequenzierung
Die Sequenzierung des menschlichen Genoms ist das kumulative Ergebnis von fast fünf Jahrzehnten internationaler Zusammenarbeit. Die... -
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
A reduced removal of dysfunctional mitochondria is common to aging and age-related neurodegenerative pathologies such as Alzheimer’s disease (AD)....
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Polymerase Chain Reaction: An Indispensable Molecular Biology Tool of 21st Century
Due to its universal applications, Polymerase Chain Reaction (PCR) became an essential technique in various scientific branches such as microbiology,...