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Silent Brain Infarction, Delirium, and Cognition in Three Invasive Cardiovascular Procedures: a Systematic Review
Silent brain infarctions (SBIs) are brain lesions noted on neuroimaging that are not associated with clinical symptoms. SBIs are associated with a...
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Parkinson’s disease CA2-CA3 hippocampal atrophy is accompanied by increased cholinergic innervation in patients with normal cognition but not in patients with mild cognitive impairment
Although brain cholinergic denervation has been largely associated with cognitive decline in patients with Parkinson’s disease (PD), new evidence...
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Sleep disorders affect cognitive function in adults: an overview of systematic reviews and meta-analyses
Sleep disorders frequently result in poor memory, attention deficits, as well as a worse prognosis for neurodegenerative changes, such as Alzheimer's...
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A plasma protein signature associated with cognitive function in men without severe cognitive impairment
BackgroundA minimally invasive blood-based assessment of cognitive function could be a promising screening strategy to identify high-risk groups for...
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Phytochemicals and Natural Extracts, Secondary Metabolites of Plants and Improvement of Brain Function
Memory, one of the most enhanced functions of human being, proclaims an activity-dependent synaptic plasticity at various synaptic levels in the... -
The effects of exercise programs on cognition, activities of daily living, and neuropsychiatric symptoms in community-dwelling people with dementia—a systematic review
BackgroundThe prevalence of dementia is expected to increase dramatically. Due to a lack of pharmacological treatment options for people with...
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Alzheimer’s pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome
BackgroundTraumatic encephalopathy syndrome (TES) is a clinical phenotype sensitive but non-specific to underlying chronic traumatic encephalopathy...
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A Liaison Brought to Light: Cerebellum-Hippocampus, Partners for Spatial Cognition
This review focuses on the functional and anatomical links between the cerebellum and the hippocampus and the role of their interplay in...
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The effects of trazodone on human cognition: a systematic review
Trazodone is a widely used antidepressant that is also useful in the control of agitation and insomnia in Alzheimer's disease. This drug is now...
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Improved cognition after rifaximin treatment is associated with changes in intra- and inter-brain network functional connectivity
BackgroundRifaximin is a non-reabsorbable antibiotic which acts at gut level, and improves cognition and inflammatory parameters in minimal hepatic...
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Sex Differences in Cognition Across Aging
Sex and gender differences are seen in cognitive disturbances in a variety of neurological and psychiatry diseases. Men are more likely to have... -
Sex differences in visuospatial cognition- a female advantage in jigsaw puzzle solving
Mentally visualizing objects, understanding relationships between two- or three- dimensional objects, and manipulating objects in space are some...
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Altered brain activity mediates the relationship between white matter hyperintensity severity and cognition in older adults
White matter hyperintensities (WMHs) on magnetic resonance imaging are commonly found in older adults. The mechanisms underpinning the...
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The effect of e-cigarettes on cognitive function: a sco** review
AimMuch research has been conducted on the acute effects of nicotine on human cognitive performance, demonstrating both enhancing and impairing...
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Effect of rs1108580 of DBH and rs1006737 of CACNA1C on Cognition and Tardive Dyskinesia in a North Indian Schizophrenia Cohort
Genetic perturbations in dopamine neurotransmission and calcium signaling pathways are implicated in the etiology of schizophrenia. We aimed to test...
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P-tau and neurodegeneration mediate the effect of β-amyloid on cognition in non-demented elders
BackgroundThere are many pathological changes in the brains of Alzheimer’s disease (AD) patients. For many years, the mainstream view on the...
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The Use of Touchscreen-Based Methods to Characterize Effects of Psychoactive Drugs on Executive Function in Nonhuman Primates
Purpose of ReviewThis review describes studies that assessed the acute and chronic effects of commonly consumed drugs on executive function, with a...
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Exogenous growth hormone administration during total sleep deprivation changed the microRNA-9 and dopamine D2 receptor expressions followed by improvement in the hippocampal synaptic potential, spatial cognition, and inflammation in rats
RationaleDisorders caused by total sleep deprivation can be modulated by the administration of growth hormone, which could affect the expression of...
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Association between APOE-ε4 allele and cognitive function is mediated by Alzheimer’s disease pathology: a population-based autopsy study in an admixed sample
BackgroundApolipoprotein E ε4 allele (APOE-ε4) is the main genetic risk factor for late-onset Alzheimer’s disease (AD) and may impact cognitive...