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Technical transfer and commercialisation of lyophilised biopharmaceuticals — application of lyophiliser characterisation and comparability
A holistic approach was taken to characterise lyophilisers at both laboratory and commercial scale to design a focused validation strategy for...
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Doxycycline Therapeutic Approach in Parkinson’s Disease and L-DOPA-Induced Dyskinesia
Parkinson’s disease is a chronic neurodegenerative disorder associated with the loss of dopamine neurons in the substantia nigra, for which there is...
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Under pressure—the influence of hypergravity on electrocortical activity and neurocognitive performance
The effects of hypergravity and the associated increased pressure on the human body have not yet been studied in detail, but are of great importance...
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LabMate: Development and Implementation of a Novel Livestreaming Platform for Hybrid or Remote Laboratory Course Delivery
Online course delivery has increased in prevalence, particularly due to the onset in 2020 of the COVID-19 pandemic. Biomedical engineering laboratory...
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Just-In-Time Education of FDA Regulation and Protection of Intellectual Property for Medical Products: A Course Review After Our First 10 Years
Successful translation of medical devices requires a clear pathway through the business environment, including regulatory obligations and the...
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Aligning Event-Related Potentials with Transcranial Alternating Current Stimulation for Modulation—a Review
This review aims to demonstrate the connections between event-related potentials (ERPs), event-related oscillations (EROs), and non-invasive brain...
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A Generalist’s Guide to Quantifying Swimming Behavior Within Traditional and Nontraditional Teleost Models
Adaptation to subterranean environments comes with striking changes to organismal behavior and metabolism. One clear example is how multiple obligate...
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Recommended Best Practices for Lyophilization Validation—2021 Part I: Process Design and Modeling
AbstractThis work describes lyophilization process validation and consists of two parts. Part I focuses on the process design and is described in the...
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Theories of consciousness
Recent years have seen a blossoming of theories about the biological and physical basis of consciousness. Good theories guide empirical research,...
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The Intelligence of the Hands
Attributing artificiality solely to technological intelligences certainly means distinguishing their capabilities from those of the human mind, whose...
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Neuroscience of taste: unlocking the human taste code
Since antiquity human taste has been divided into 4–5 taste qualities. We realized in the early 1970s that taste qualities vary between species and...
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Deep or Shallow? A Comparative Analysis on the Oil Species Identification Based on Excitation-Emission Matrix and Multiple Machine Learning Algorithms
With the continuous expansion of petroleum extraction, transportation, and storage, the risk of oil spills at sea has also increased, posing a...
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An Experimental Phototherapy Device for Studying the Effects of Blue Light on Patients with Raynaud’s Phenomenon
Raynaud’s phenomenon (RP) is a condition that causes decreased blood flow to areas perfused by small blood vessels (e.g., fingers, toes). In severe...
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Neural Endophenotype Assessment in Zebrafish Larvae Using Optomotor and ZebraBox Locomotion Assessment
Due to the highly conserved genetics across the central nervous system, the easily probed visual system can act as an endophenotype for assessing...
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Head Impact Location, Speed and Angle from Falls and Trips in the Workplace
Traumatic brain injury (TBI) is a common injury in the workplace. Trips and falls are the leading causes of TBI in the workplace. However, industrial...
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High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations
Genetically encoded voltage indicators (GEVIs) hold immense potential for monitoring neuronal population activity. To date, best-in-class GEVIs rely...
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Deconvolution of the Functional Ultrasound Response in the Mouse Visual Pathway Using Block-Term Decomposition
Functional ultrasound (fUS) indirectly measures brain activity by detecting changes in cerebral blood volume following neural activation....
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The test–retest reliability of physiological and perceptual responses during treadmill load carriage
PurposeUnderstanding the test–retest reliability of physiological responses to load carriage influences the interpretation of those results. The aim...
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Characterizing Natural Frequencies of the Hybrid III and NOCSAE Headforms
The vibrational characteristics of the Hybrid III and NOCSAE headforms are not well understood. It is hypothesized that they may perform differently...
