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Wharton’s jelly mesenchymal stem cells transplantation for critical limb ischemia in patients with type 2 diabetes mellitus: a preliminary report of phase I clinical trial
Peripheral artery disease (PAD) affects more than 230 million people worldwide, with approximately 11% of patients presenting with advanced-stage PAD...
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Clinical manifestations, prognostic factors, and outcomes of adenovirus pneumonia after allogeneic hematopoietic stem cell transplantation
BackgroundSevere pneumonia is one of the most important causes of mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT)....
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Pathobiological signatures of dysbiotic lung injury in pediatric patients undergoing stem cell transplantation
Hematopoietic cell transplantation (HCT) uses cytotoxic chemotherapy and/or radiation followed by intravenous infusion of stem cells to cure...
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Bio-artificial pleura using autologous dermal fibroblast sheets to mitigate air leaks during thoracoscopic lung resection
Lung air leaks (LALs) due to visceral pleura injury during surgery are a difficult-to-avoid complication in thoracic surgery (TS). Reliable LAL...
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Outcomes of renal transplantation in patients with AL amyloidosis: an international collaboration through The International Kidney and Monoclonal Gammopathy Research Group
Effective systemic therapies suppress toxic light chain production leading to an increased proportion of patients with light chain (AL) amyloidosis...
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Stem cell transplantation as a progressing treatment for retinitis pigmentosa
Retinal degenerative diseases such as retinitis pigmentosa (RP) are of the major causes of vision loss in developed countries. Despite the unclear...
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Feasibility of implementing a supervised telehealth exercise intervention in frail survivors of hematopoietic cell transplantation: a pilot randomized trial
BackgroundPatients undergoing hematopoietic cell transplantation (HCT) are at high risk of chronic health complications, including frailty and...
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Mitochondrial transplantation therapy for ischemia reperfusion injury: a systematic review of animal and human studies
BackgroundMitochondria are essential organelles that provide energy for cellular functions, participate in cellular signaling and growth, and...
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CTLA4-Ig alleviates the allogeneic immune responses against insulin-producing cells in a murine model of cell transplantation
The adoptive transfer of insulin-producing cells (IPCs) is one of the promising treatments for insulin-dependent diabetes mellitus. While the use of...
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Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation
A primary goal in transplantation medicine is the induction of a tolerogenic environment for prevention of transplant rejection without the need for...
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Nomogram for Predicting Early Mortality after Umbilical Cord Blood Transplantation in Children with Inborn Errors of Immunity
PurposePediatric patients with inborn errors of immunity (IEI) undergoing umbilical cord blood transplantation (UCBT) are at risk of early mortality....
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Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis
PurposeNon-tuberculous mycobacteria (NTM) infections in hematopoietic stem cell transplantation (HSCT) recipients represent a diagnostic and...
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Post-transplant cyclophosphamide versus anti-thymocyte globulin after reduced intensity peripheral blood allogeneic cell transplantation in recipients of matched sibling or 10/10 HLA matched unrelated donors: final analysis of a randomized, open-label, multicenter, phase 2 trial
The use of post-transplantation cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis is not established after reduced intensity...
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Mitochondrial Transplantation for Ischemia Reperfusion Injury
Mitochondrial transplantation is a novel therapeutic intervention to treat ischemia-reperfusion-related disorders. This approach uses replacement of...
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Donor CSF3R with the rs3917980A/G or G/G genotype is correlated with better leukemia-free survival after allogenic hematopoietic stem cell transplantation
Polymorphisms in the granulocyte colony-stimulating factor receptor gene (GCSFR, CSF3R) have been reported to be associated with peripheral blood...
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Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings
In the regenerative medicine field, allogenic transplantation of regenerated tissues has been promoted because autologous transplantation setting is...
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Cerebellar Transplantation: A Potential Model to Study Repair and Development of Neurons and Circuits in the Cerebellum
Neuronal transplantation offers a unique experimental situation for the in vivo study of cell-to-cell interactions between embryonic and adult neural...
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One step forward: extracellular mitochondria transplantation
Mitochondria play a key role in cellular energy production and contribute to cell metabolism, homeostasis, intracellular signalling and organelle’s...
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Hepatocyte organoids and cell transplantation: What the future holds
Historically, primary hepatocytes have been difficult to expand or maintain in vitro. In this review, we will focus on recent advances in...
