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1. Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics

   Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult...

   Chirine El-Baba, Ali H. Eid, ... Nadine Darwiche in Handbook of Oxidative Stress in Cancer: Mechanistic Aspects

   Reference work entry 2022
   

2. The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

   Background

   MYCN is amplified in small cell lung cancers and several pediatric tumors, including alveolar rhabdomyosarcomas and neuroblastomas. MYCN...

   Eleanor M. O’Brien, Joanna L. Selfe, ... Janet M. Shipley in BMC Cancer

   Article Open access 21 February 2018
   

3. Mechanisms Underlying HFMD Clinical Pathology in Children

   Hand, foot, and mouth disease (HFMD) is generally recognized as a contagious viral disease that commonly occurs in children worldwide, with a high...

   **ngli Xu in Molecular Biology of Hand-Foot-Mouth Diseases

   Chapter 2024
   

4. Soft tissue masses: distribution of entities and rate of malignancy in small lesions

   Background

   Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this...

   Felix G. Gassert, Florian T. Gassert, ... Klaus Woertler in BMC Cancer

   Article Open access 22 January 2021
   

5. Advanced Therapeutic Approaches in Cancer Therapy

   Recent advancements in cancer research have led to improved methods for early detection, prognostic monitoring, and innovative therapeutic...

   Ranbir Chander Sobti, Sunil Babu Gosipatala, ... Manish Thakur in Handbook of Oncobiology: From Basic to Clinical Sciences

   Living reference work entry 2024
   

6. Advanced Therapeutic Approaches in Cancer Therapy

   Recent advancements in cancer research have led to improved methods for early detection, prognostic monitoring, and innovative therapeutic...

   R. C. Sobti, Sunil Babu Gosipatala, ... Manish Thakur in Handbook of Oncobiology: From Basic to Clinical Sciences

   Reference work entry 2024
   

7. CCL24 Signaling in the Tumor Microenvironment

   Chemokines with their network play an important role in cancer growth, metastasis, and host-tumor interactions. Of many chemokines, C-C motif...

   Sung-Jig Lim in Tumor Microenvironment

   Chapter 2021
   

8. Is immunotherapy in the future of therapeutic management of sarcomas?

   Sarcomas are rare, ubiquitous and heterogeneous tumors usually treated with surgery, chemotherapy, target therapy, and radiotherapy. However, 25–50%...

   Ottavia Clemente, Alessandro Ottaiano, ... Salvatore Tafuto in Journal of Translational Medicine

   Article Open access 26 April 2021
   

9. GLP and G9a histone methyltransferases as potential therapeutic targets for lymphoid neoplasms

   Histone methyltransferases (HMTs) are enzymes that regulate histone methylation and play an important role in controlling transcription by altering...

   Amandda Évelin Silva-Carvalho, Luma Dayane Carvalho Filiú-Braga, ... Felipe Saldanha-Araujo in Cancer Cell International

   Article Open access 12 July 2024
   

10. PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study

    Background

    Rhabdomyosarcomas (RMSs) are the most frequent soft tissue sarcoma in children and adolescents, defined by skeletal muscle differentiation...

    Giulia Bertolini, Luca Bergamaschi, ... Patrizia Gasparini in BMC Cancer

    Article Open access 13 June 2018
    

11. Protocol for the 2ND-STEP study, Japan Clinical Oncology Group study JCOG1802: a randomized phase II trial of second-line treatment for advanced soft tissue sarcoma comparing trabectedin, eribulin and pazopanib

    Background

    Soft tissue sarcomas (STS) are a rare type of malignancy comprising a variety of histological diagnoses. Chemotherapy constitutes the...

    Makoto Endo, Tomoko Kataoka, ... Kazuhiro Tanaka in BMC Cancer

    Article Open access 08 March 2023
    

12. Assessment of Synergistic Contribution of Histone Deacetylases in Prognosis and Therapeutic Management of Sarcoma

    Sarcomas are a rare group of neoplasms with a mesenchymal origin that are mainly characterized by the abnormal growth of connective tissue cells. The...

    Aikaterini Mastoraki, Dimitrios Schizas, ... Emmanouil Pikoulis in Molecular Diagnosis & Therapy

    Article 21 July 2020
    

13. Distinct nitrogen isotopic compositions of healthy and cancerous tissue in mice brain and head&neck micro-biopsies

    Background

    Cancerous cells can recycle metabolic ammonium for their growth. As this ammonium has a low nitrogen isotope ratio ( ¹⁵ N/ ¹⁴ N), its...

    M. Straub, D. M. Sigman, ... A. Martínez-García in BMC Cancer

    Article Open access 13 July 2021
    

14. Single-Cell RNAseq Analysis of lncRNAs

    Mammalian genomes are pervasively transcribed and a small fraction of RNAs produced codify for proteins. The importance of noncoding RNAs for the...

    Stefano Cagnin, Enrico Alessio, ... Gabriele Sales in Long Non-Coding RNAs in Cancer

    Protocol 2021
    

15. A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301)

    Purpose

    5-fluorouracil (5-FU) is inefficiently converted to the active anti-cancer metabolite, fluorodeoxyuridine-monophosphate (FUDR-MP), is...

    Pavlina Spiliopoulou, Farasat Kazmi, ... Sarah P. Blagden in Journal of Experimental & Clinical Cancer Research

    Article Open access 02 April 2024
    

16. Chromosomal instability (CIN) in HAP1 cell lines revealed by multiplex fluorescence in situ hybridisation (M-FISH)

    Background

    HAP1, a near-haploid human leukemic cancer cell line is often used in combination with CRISPR-Cas9 gene editing technology for genetic...

    Ruby Banerjee, Cibele G. Sotero-Caio, ... Fengtang Yang in Molecular Cytogenetics

    Article Open access 26 October 2022
    

17. Tumor Immune Microenvironment of Soft Tissue Sarcoma

    Soft tissue sarcoma (STS) is a group of cancers transformed from mesenchymal cells. The treatment outcome of immunotherapy has not been as successful...

    Tom Wei-Wu Chen, Sheng-Fang Su, William W. Tseng in Cancer Metastasis Through the Lymphovascular System

    Chapter 2022
    

18. Fibroblast Growth Factors

    Paola Chiodelli, Marco Presta in Encyclopedia of Molecular Pharmacology

    Living reference work entry 2021
    

19. Fibroblast Growth Factors

    Paola Chiodelli, Marco Presta in Encyclopedia of Molecular Pharmacology

    Reference work entry 2021
    

20. Roles of Sialyl Glycans in HCoV-OC43, HCoV-HKU1, MERS-CoV and SARS-CoV-2 Infections

    Ongoing seasonal HCoV-OC43 and HCoV-HKU1 (common cold), an ongoing zoonotic infection of highly lethal MERS-CoV in humans (MERS disease), and an...

    Nongluk Sriwilaijaroen, Yasuo Suzuki in Glycovirology

    Protocol 2022