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Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase
Hypothyroidism causes learning and memory impairment. Considering the neuroprotective properties of thiamine (Vitamin B1), this study was conducted...
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Response of the Hemostatic System to Acute Vital Stress in Rats
We studied the effect of acute vital stress on the parameters of the hemostasis system in young and old Wistar rats. The psychotraumatic effect was...
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Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding
BackgroundWhen feeding on a vertebrate host, ticks secrete saliva, which is a complex mixture of proteins, lipids, and other molecules. Tick saliva...
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Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of...
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Aquaporins in Skin
The skin is the largest organ of our body and plays a protective role against the external environment. The skin functions as a mechanical and water...
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Role of palliative radiotherapy in bleeding control in patients with unresectable advanced gastric cancer
BackgroundThis study analyzed the clinical results of palliative radiotherapy for bleeding control in patients with unresectable advanced gastric...
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A novel sight of the primary active compounds from Umbelliferae: focusing on mitochondria
Mitochondria perform diverse interconnected functions, participating in energy metabolism, oxidative stress, calcium hemostasis, and apoptosis. It is...
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Interplay Between Cancer, Platelets, and Megakaryocytes During Metastasis
Besides their contribution to hemostasis and wound healing, platelets and their precursors megakaryocytes have a prominent role in cancer progression...
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Intraoperative Detection of Surgical Gauze Using Deep Convolutional Neural Network
During laparoscopic surgery, surgical gauze is usually inserted into the body cavity to help achieve hemostasis. Retention of surgical gauze in the...
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A novel insight into mechanism of derangement of coagulation balance: interactions of quantum dots with coagulation-related proteins
BackgroundQuantum dots (QDs) have gained increased attention for their extensive biomedical and electronic products applications. Due to the high...
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Endothelial cells and coagulation
Endothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled...
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Hydrogen sulfide supplement preserves mitochondrial function of retinal ganglion cell in a rat glaucoma model
Glaucoma is a neurodegenerative disease of visual system characterized by gradual loss of retinal ganglion cells (RGC). Since mitochondrial...
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The Role of Thrombin in Brain Injury After Hemorrhagic and Ischemic Stroke
Thrombin is increased in the brain after hemorrhagic and ischemic stroke primarily due to the prothrombin entry from blood either with a hemorrhage...
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Study of sympathetic skin response in patients with COVID-19 infection
ObjectivesMany articles hypothesized the potential role of autonomic nervous system in the pathogenesis and outcome of COVID-19 infection. Several...
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Protocol for a confirmatory trial of the effectiveness and safety of palliative arterial embolization for painful bone metastases
BackgroundTranscatheter arterial embolization (TAE) has long been used for hemostasis of traumatic or postoperative hemorrhage and embolization of...
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Non-clinical investigations about cytotoxic and anti-platelet activities of gamma-terpinene
Gamma-terpinene (γ-TPN) is a cyclohexane monoterpene isolated from plant essential oils, such as tea tree ( Melaleuca alternifolia ), oregano ( Origanum...
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Purinergic interplay between erythrocytes and platelets in diabetes-associated vascular dysfunction
Cardiovascular complications in diabetes are the leading causes for high morbidity and mortality. It has been shown that alteration of purinergic...
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The contact system in liver injury
Coagulation is controlled by a delicate balance of prothrombotic and antithrombotic mechanisms, to prevent both excessive blood loss from injured...
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Role of platelet biomarkers in inflammatory response
Beyond hemostasis, thrombosis and wound healing, it is becoming increasingly clear that platelets play an integral role in inflammatory response and...
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Computational Modeling of the Coagulation Response During Trauma
Coagulation and platelet aggregation are the primary mechanisms for maintaining hemostasis upon traumatic injury. However, prolonged bleeding may...