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Showing 61-80 of 10,000 results
  1. Central autonomic network dysfunction and plasma Alzheimer’s disease biomarkers in older adults

    Background

    Higher order regulation of autonomic function is maintained by the coordinated activity of specific cortical and subcortical brain regions,...

    Trevor Lohman, Arunima Kapoor, ... Daniel A. Nation in Alzheimer's Research & Therapy
    Article Open access 08 June 2024
  2. Can adults with developmental dyslexia apply statistical knowledge to a new context?

    We investigated transfer of artificial grammar learning in adults with and without dyslexia in 3 experiments. In Experiment 1, participants...

    Rachel Schiff, Hadar Cohen, ... Ayelet Sasson in Cognitive Processing
    Article 07 November 2022
  3. Explaining the influence of practice on the grooved pegboard times of older adults: role of force steadiness

    The purpose was to identify the variables that can explain the variance in the grooved pegboard times of older adults categorized as either fast or...

    Sajjad Daneshgar, Taylor Tvrdy, Roger M. Enoka in Experimental Brain Research
    Article 25 June 2024
  4. Long-term Tai Chi training reduces the fusion illusion in older adults

    Sound-induced flash illusion (SiFI) is an auditory-dominated audiovisual integration phenomenon that can be used as a reliable indicator of...

    Aijun Wang, Tingting Wang, ... Ming Zhang in Experimental Brain Research
    Article 08 January 2023
  5. Assessing Dose-Exposure–Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach

    Objectives

    Miltefosine is the first and only oral medication to be successfully utilized as an antileishmanial agent. However, the drug is associated...

    Shadrack J. Madu, Ke Wang, ... Mingzhong Li in Pharmaceutical Research
    Article Open access 10 October 2023
  6. Osteomyelitis caused by Streptococcus intermedius in immunocompetent adults — a case report and systematic literature review

    Hematogenous osteomyelitis caused by Streptococcus intermedius is rare, particularly in immunocompetent adults. The aim of this paper is to provide...

    Elyne M. Brunink, Lotje A. Hoogervorst, ... Mark G. J. de Boer in European Journal of Clinical Microbiology & Infectious Diseases
    Article Open access 20 July 2023
  7. Circulating MiRNAs Are Associated With Low-grade Systemic Inflammation and Leptin Levels in Older Adults

    Inflammaging refers to the low-grade systemic inflammation that occurs with aging present in chronic non-communicable diseases. MicroRNAs (miRNAs)...

    Gabrielli B. Carvalho, Paula N. Brandão-Lima, ... Marcelo M. Rogero in Inflammation
    Article 19 July 2023
  8. Methamphetamine alters nucleus accumbens neural activation to monetary loss in healthy young adults

    Rationale

    Stimulant drugs like methamphetamine (MA) activate brain reward circuitry, which is linked to the development of problematic drug use. It is...

    Natania A. Crane, Hanna Molla, Harriet de Wit in Psychopharmacology
    Article 02 August 2023
  9. Healthy adults favor stable left/right hand choices over performance at an unconstrained reach-to-grasp task

    Reach-to-grasp actions are fundamental to the daily activities of human life, but few methods exist to assess individuals’ reaching and gras**...

    Taewon Kim, Ruiwen Zhou, ... Benjamin A. Philip in Experimental Brain Research
    Article 02 April 2024
  10. Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults

    Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However,...

    Bernardo Abel Cedeno-Veloz, Lucía Lozano-Vicario, ... Nicolás Martínez-Velilla in Immunity & Ageing
    Article Open access 18 October 2023
  11. Insomnia complaints correlated with higher risk of cognitive impairment in older adults following stroke: a National Representative Comparison Study

    Although associations among insomnia, cognitive impairment, and stroke have been demonstrated, whether insomnia increases the risk of cognitive...

    Wei Liang, Dean Wu, ... Hsiao-Yean Chiu in Sleep and Biological Rhythms
    Article 18 July 2023
  12. Fall risk classification with posturographic parameters in community-dwelling older adults: a machine learning and explainable artificial intelligence approach

    Background

    Computerized posturography obtained in standing conditions has been applied to classify fall risk for older adults or disease groups....

    Huey-Wen Liang, Rasoul Ameri, ... Arthur Chang in Journal of NeuroEngineering and Rehabilitation
    Article Open access 29 January 2024
  13. Integrated cognitive and physical fitness training enhances attention abilities in older adults

    Preserving attention abilities is of great concern to older adults who are motivated to maintain their quality of life. Both cognitive and physical...

    Joaquin A. Anguera, Joshua J. Volponi, ... Adam Gazzaley in npj Aging
    Article Open access 30 August 2022
  14. Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults

    Background

    Immune responses to COVID-19 mRNA vaccines have not been well characterized in frail older adults. We postulated that frailty is associated...

    Charles T. Semelka, Michael E. DeWitt, ... Martha A. Alexander-Miller in Immunity & Ageing
    Article Open access 17 January 2023
  15. Limited training and transfer effects in older and young adults who participated in 12 sessions of process-based working memory training. A three-armed pretest-posttest design study

    Objective

    Numerous studies confirm the effectiveness of cognitive training in older adults. However, there is limited evidence of the transfer...

    Ludmiła Zając-Lamparska in BMC Research Notes
    Article Open access 28 June 2024
  16. Inter-day reliability of heart rate complexity and variability metrics in healthy highly active younger and older adults

    Purpose

    To investigate the inter-day reliability of time-domain, frequency-domain, and nonlinear HRV metrics in healthy highly active younger and...

    Christopher R. J. Fennell, Alexis R. Mauger, James G. Hopker in European Journal of Applied Physiology
    Article Open access 06 December 2023
  17. Determinants of COVID-19 vaccination status and hesitancy among older adults in China

    Vaccination is the primary defense against severe acute respiratory syndrome coronavirus 2, especially among older adults and those with chronic...

    Gewei Wang, Yao Yao, ... Yaohui Zhao in Nature Medicine
    Article 31 January 2023
  18. Characterization of B-cell and T-cell responses to a tetravalent dengue purified inactivated vaccine in healthy adults

    The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following...

    Heather Friberg, Morgan Gargulak, ... Jeffrey R. Currier in npj Vaccines
    Article Open access 31 October 2022
  19. Integrated Exposure–Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis

    Background

    While the majority of patients with atopic dermatitis (AD) achieve disease control with dupilumab treatment, there is variability in which...

    Emily Briggs, Mohamed A. Kamal, ... Nidal Huniti in Pharmaceutical Research
    Article Open access 01 November 2023
  20. Two-week step-reduction has limited negative effects on physical function and metabolic health in older adults

    Purpose

    This study determined the effects of a 2-week step-reduction period followed by 4-week exercise rehabilitation on physical function, body...

    Simon Walker, Ulla-Maria Sahinaho, ... Maarit Lehti in European Journal of Applied Physiology
    Article Open access 21 February 2024
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