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Tremor in Childhood
Tremor particularly affects the upper limbs but can involve almost any part of the body including the head, face, eyelids, tongue, vocal cords, and... -
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The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial
Non-alcoholic fatty liver disease (NAFLD) is a global health problem with increasing prevalence among overweight and obese patients. It is strongly... -
Image-based state-of-the-art techniques for the identification and classification of brain diseases: a review
Detection and classification methods have a vital and important role in identifying brain diseases. Timely detection and classification of brain...
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Identification and characterization of a novel 43-bp deletion mutation of the ATP7B gene in a Chinese patient with Wilson’s disease: a case report
BackgroundWilson’s disease (WD) is an autosomal recessive disorder characterized by copper accumulation. ATP7B gene mutations lead to ATP7B protein...
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Tremor: The Clinical Approach to Reach the Diagnosis
A systematic approach with a focus on the anatomic location, activating conditions, and phenomenology is needed to accurately diagnose tremor. A... -
An Assessment of the Serum Activity of ADH and ALDH in Patients with Primary Biliary Cholangitis
Primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis) is a chronic inflammation-induced cholestatic process in the liver....
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Circulating histone signature of human lean metabolic-associated fatty liver disease (MAFLD)
BackgroundAlthough metabolic associate fatty liver disease (MAFLD) is associated with obesity, it can also occur in lean patients. MAFLD is more...
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Ataxia in a Movement Disorders Outpatient Clinic: a Single-Center Experience in Turkey
The etiology may not be determined in patients with ataxia despite detailed evaluations. The aim of this study was to investigate the clinical and...
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Rest Tremor
By definition, rest tremor is an involuntary oscillation occurring while the body segment is maintained at rest, fully supported against gravity. To... -
Metabolic Causes of Tremor
Metabolic causes of tremor include systemic metabolic, neurometabolic, and endocrine abnormalities. These can be diagnosed by identification of... -
Physiological Recordings of the Cerebellum in Movement Disorders
The cerebellum plays an important role in movement disorders, specifically in symptoms of ataxia, tremor, and dystonia. Understanding the...
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Basal Ganglia: Basic Principles
The full range of basal ganglia functions is still uncertain, but they are principally concerned with the release and suppression of cortically... -
The Relationships Among Metal Homeostasis, Mitochondria, and Locus Coeruleus in Psychiatric and Neurodegenerative Disorders: Potential Pathogenetic Mechanism and Therapeutic Implications
While alterations in the locus coeruleus-noradrenergic system are present during early stages of neuropsychiatric disorders, it is unclear what...
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A novel ceruloplasmin mutation identified in a Chinese patient and clinical spectrum of aceruloplasminemia patients
Aceruloplasminemia (ACP) is a rare disorder of iron overload resulting from ceruloplasmin ( CP ) variants. Because of its rarity and heterogeneity, the...
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Functionalized Green Carbon dots for Specific Detection of Copper in Human Serum Samples and Living Cells
Intracellular copper ion (Cu 2+ ) is irreplaceable and essential in regulation of physiological and biological processes, while excessive copper from...
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Immunomodulation of cuproptosis and ferroptosis in liver cancer
According to statistics, the incidence of liver cancer is increasing yearly, and effective treatment of liver cancer is imminent. For early liver...
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Choroid plexus and the blood–cerebrospinal fluid barrier in disease
The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the least studied structures of the central nervous system...