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Viruses and cells intertwined since the dawn of evolution
Many attempts have been made to define nature of viruses and to uncover their origin. Our aim within this work was to show that there are different...
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A classification system for virophages and satellite viruses
Satellite viruses encode structural proteins required for the formation of infectious particles but depend on helper viruses for completing their...
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A Decade of Giant Virus Genomics: Surprising Discoveries Opening New Questions
During the last decade, viral studies have investigated truly large viruses for the first time in the history of biology. Those giants of viruses... -
Samba virus: a novel mimivirus from a giant rain forest, the Brazilian Amazon
BackgroundThe identification of novel giant viruses from the nucleocytoplasmic large DNA viruses group and their virophages has increased in the last...
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Comparative metagenomic analyses reveal viral-induced shifts of host metabolism towards nucleotide biosynthesis
BackgroundViral genomes often contain metabolic genes that were acquired from host genomes (auxiliary genes). It is assumed that these genes are...
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Tetraspanins as Facilitators of Viral and Cellular Information Transfer
Cells that are infected by a virus can infect other cells by passing on the viral genome. Such transfer of viral genetic information can occur by... -
Combined Approaches to Study Virus Structures
A virus particle must work as a safe box for protecting its genome, but at the same time it has to undergo dramatic conformational changes in order... -
Hidden evolutionary complexity of Nucleo-Cytoplasmic Large DNA viruses of eukaryotes
BackgroundThe Nucleo-Cytoplasmic Large DNA Viruses (NCLDV) constitute an apparently monophyletic group that consists of at least 6 families of...
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A new proposed taxon for double-stranded DNA viruses, the order “Ligamenvirales”
Linear viruses with double-stranded DNA genomes are classified into two families, Lipothrixviridae and Rudiviridae . The members of these two...
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Introduction and Historical Perspective
The discoveries of DNA supercoiling and DNA topoisomerases have been two of the most important breakthroughs in biology in the last century. Negative... -
A novel adenovirus of Western lowland gorillas (Gorilla gorilla gorilla)
Adenoviruses (AdV) broadly infect vertebrate hosts including a variety of primates. We identified a novel AdV in the feces of captive gorillas by...
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Analysis of a new strain of Euphorbia mosaic virus with distinct replication specificity unveils a lineage of begomoviruses with short Rep sequences in the DNA-B intergenic region
BackgroundEuphorbia mosaic virus (EuMV) is a member of the SLCV clade, a lineage of New World begomoviruses that display distinctive features in...