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Development and Characterization of Saturated Fatty Acid-Engineered, Silica-Coated Lipid Vesicular System for Effective Oral Delivery of Alfa-Choriogonadotropin
The present study was designed to develop an efficient, safe, and patient-friendly dosage form, for oral delivery of alfa-choriogonadotropin, used in...
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Visual Monitoring of Disintegration of Solid Oral Dosage Forms in Simulated Gastric Fluids Using Low-Field NMR Imaging
Compared to traditional drug release monitoring with manual sampling and testing procedures, low-field nuclear magnetic resonance (LF-NMR) imaging is...
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Azithromycin-loaded linolenic acid-modified methoxy poly(ethylene glycol) micelles for bacterial infection treatment
In the study, new polymeric micelles loaded with azithromycin were prepared to enhance azithromycin’s solubility and evaluate its in vitro/in vivo...
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Implementing Nanovesicles for Boosting the Skin Permeation of Non-steroidal Anti-inflammatory Drugs
The consumption of non-steroidal anti-inflammatory drugs (NSAIDs) have increased lately around the world, as they are considered essential and...
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Liposomes for the Management of Allergic Airway Diseases
To treat allergic airway illnesses, lipid-based vesicles called liposomes can be employed as drug delivery vehicles. Asthma, allergic rhinitis, and... -
Formulation of Saxagliptin Oral Films: Optimization, Physicochemical Characterization, In-Vivo Assessment, and In-Vitro Real-Time Release Monitoring via a Novel Polyaniline Nanoparticles-Based Solid-Contact Screen Printed Ion-Selective Electrode
Oral dispersible films have received broad interest due to fast drug absorption and no first-path metabolism, leading to high bioavailability and...
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Unlocking the Potential of Bilosomes and Modified Bilosomes: a Comprehensive Journey into Advanced Drug Delivery Trends
Vesicular drug delivery systems have revolutionized the pharmaceutical field, offering a promising path for achieving targeted and sustained drug...
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Nano/microformulations for Bacteriophage Delivery
Encapsulation methodologies allow the protection of bacteriophages for overcoming critical environmental conditions. Moreover, they improve the... -
RETRACTED ARTICLE: Oral Bioavailability Improvement of Tailored Rosuvastatin Loaded Niosomal Nanocarriers to Manage Ischemic Heart Disease: Optimization, Ex Vivo and In Vivo Studies
Rosuvastatin is an efficient antihyperlipidemic agent; however, being a BCS class II molecule, it shows poor oral bioavailability of < 20%. The...
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Design, Development, and Evaluation of SA-F127:TPGS Polymeric Mixed Micelles for Improved Delivery of Glipizide Drug: In-vitro, Ex-vivo, and In-vivo Investigations
The anti-diabetic glipizide (GLN) drug has notable pharmaceutical advantages, but poor aqueous solubility restricts its wide applications. The...
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Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications
The application of nanotechnology with integration of chemical sciences is increasing continuously in the management of diseases. The drug’s...
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Lipid-Based Vesicles: a Non-invasive Tool for Transdermal Drug Delivery
The emergence of lipid nanovesicles (LNVs), like liposomes, transferosomes, and ethosomes, strengthens transdermal drug delivery. The composition of...
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Development and Characterization of Bioadhesive Film Embedded with Lignocaine and Calcium Fluoride Nanoparticles
The formation of biofilm by Streptococcus mutans on the tooth surface is the primary cause of dental caries and periodontal diseases, and fluoride...
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Cyclodextrins and their potential applications for delivering vitamins, iron, and iodine for improving micronutrient status
Cyclodextrins (CDs) have been investigated as potential biopolymeric carriers that can form inclusion complexes with numerous bioactive ingredients....
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Connexin-Containing Vesicles for Drug Delivery
Connexin is a transmembrane protein present on the cell membrane of most cell types. Connexins assemble into a hexameric hemichannel known as...
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Formulation, Development, and Comparative Study of Azelastine-Loaded Temperature Sensitive In Situ Gelling Micelles for Allergic Conjunctivitis
PurposeThe current investigative study was performed to analyze and compare the effect of gellan gum-mixed poloxamer 407 as compared to plain...
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Vesicular Nanomaterials: Types and Therapeutic Uses
Nanomaterials are defined as materials of nanoscale dimensions (<100 nm) manufactured via various nanotechnology based techniques. In pharmaceutical... -
Preparation, characterization, and evaluation of eosin B–loaded nano-liposomes for growth inhibition of Plasmodium falciparum
Malaria is a deadly disease in humans caused by the Plasmodium parasite. High prevalence of malaria and resistance of malaria parasite to currently...
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Luliconazole Nail Lacquer for the Treatment of Onychomycosis: Formulation, Characterization and In Vitro and Ex Vivo Evaluation
Onychomycosis is the most common fungal infection of the nail affecting the skin under the fingertips and the toes. Currently, available therapy for...
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A chitosan film containing quercetin-loaded transfersomes for treatment of secondary osteoporosis
Osteoporosis, due to its prevalence worldwide, is a serious health problem. Topical administration of quercetin, a phytoestrogen, in the form of...