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Melanin Based Classification of Skin Types and Their Susceptibility to UV-Induced Cancer
One of the characteristics that easily distinguish every human being is their skin complexion. The primary pigment that brings about this distinction...
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Differential Regional Responses in Soluble Monomeric Alpha Synuclein Abundance Following Traumatic Brain Injury
Alpha synuclein (α-synuclein) is a neuronal protein found predominately in presynaptic terminals. While the pathological effect of α-synuclein...
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Chronic Wounds: An Overview of Wound Healing and Experimental Models for Wound Studies
Wound management remains a significant healthcare burden worldwide. The search is ongoing for new treatment options for infected and hard-to-heal...
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BDNF and Lactate as Modulators of Hippocampal CA3 Network Physiology
Growing evidence supports the notion that brain-derived neurotrophic factor (BDNF) and lactate are potent modulators of mammalian brain function. The...
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The Mouse Hippocampus
The hippocampus is the phylogenetically second oldest part of the telencephalon after the olfactory system (Chap. 14). The rodent hippocampus is a...
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Dynamic Foot Stimulations During Short-Term Hindlimb Unloading Prevent Dysregulation of the Neurotransmission in the Hippocampus of Rats
Spaceflight and simulated microgravity both affect learning and memory, which are mostly controlled by the hippocampus. However, data about molecular...
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Design of Experiments for the Development of Topical Drug Products
The systematic development of pharmaceutical products using quality tools is highly essential for attaining robust performance by minimizing...
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Fungal Polysaccharide Production for Dermatological Purposes
Bioactive polysaccharides such as β-glucans are important structural component of cell wall in practically all fungi. To obtain these substances is...
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Glyphosate exposure induces synaptic impairment in hippocampal neurons and cognitive deficits in develo** rats
Glyphosate is the active ingredient of several widely used herbicide formulations. Studies based on Glyphosate exposure in different experimental...
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Basic Science
This chapter review the embryology, anatomy, and basic science of the components of the skin and subcutaneous tissue.
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Metal Nanoparticle Based Antibacterial Nanocomposites for Skin Infections
There are ample numbers of patients who have been suffering from skin and soft tissue infections (SSTIs) all over the world. Development of SSTIs...
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The habenula-targeting neurons in the mouse entopeduncular nucleus contain not only somatostatin-positive neurons but also nitric oxide synthase-positive neurons
The entopeduncular nucleus (EPN) in rodents is one of the two major output nuclei of the basal ganglia and corresponds to the internal segment of the...
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Expression Pattern of ALOXE3 in Mouse Brain Suggests Its Relationship with Seizure Susceptibility
Arachidonic acid (AA), a polyunsaturated fatty acid, is involved in the modulation of neuronal excitability in the brain. Arachidonate lipoxygenase 3...
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NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation
Kainate type ionotropic glutamate receptors (KARs) are expressed in hippocampal interneurons and regulate interneuron excitability and GABAergic...
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Glial Cell Abnormalities in Major Psychiatric Diseases: A Systematic Review of Postmortem Brain Studies
There have been a large number of reports about glial cell dysfunction being related to major psychiatric diseases such as schizophrenia (SCZ),...
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Early Aberrant Growth of Mossy Fibers after Status Epilepticus in the Immature Rat Brain
Axonal sprouting is recognized to be an important mean of repair after neurologic injury. Some characteristic aftermaths of pilocarpine-induced...
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GABAergic deficits in absence of LPA1 receptor, associated anxiety-like and co** behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus
Defects in GABAergic function can cause anxiety- and depression-like behaviors among other neuropsychiatric disorders. Therapeutic strategies using...
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Transdermal Delivery Systems for Biomolecules
PurposeThe present review article focuses on highlighting the main technologies used as tools that improve the delivery of transdermal biomolecules,...
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Shaker-related voltage-gated potassium channels Kv1 in human hippocampus
In this study, we investigated the tissue expression levels, alpha subunit composition and distribution of Shaker-related voltage-dependent potassium...
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Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies
BackgroundAir pollution is killing close to 5 million people a year, and harming billions more. Air pollution levels remain extremely high in many...
