Search
Search Results
-
Charles H. Phoenix
Charles H. Phoenix was a scientist whose most notable work investigated the role of sex steroidsSex steroids on the organizational role of the...
-
Skeletal Muscle Fiber Type and Morphology in a Middle-Aged Elite Male Powerlifter Using Anabolic Steroids
Powerlifting regularly exposes athletes to extreme stimuli such as chronic heavy resistance training (HRT), and many powerlifters choose to augment...
-
Post-SARS-CoV-2 Atypical Inflammatory Syndrome in a Toddler with X-Linked Inhibitor of Apoptosis Deficiency After Stem Cell Transplant
A 10-month-old boy was diagnosed with X-linked lymphoproliferative syndrome type 2 due to X-linked inhibitor of apoptosis deficiency after presenting...
-
Sex differences in song syntax and syllable diversity in testosterone-induced songs of adult male and female canaries
BackgroundBehavioral sex differences are widespread in the animal world. These differences can be qualitative (i.e., behavior present in one sex but...
-
A comparative study of biological and chemical composition of African spinach (Amaranthus cruentus) extract: an approach in drug formulation, food and nutrition
African spinach ( Amaranthus cruentus ) is an edible-leaved member of the pigweed family grown widely in Africa as a cooked green vegetable. This...
-
Rosehip tea as a possible cause of acute interstitial nephritis
BackgroundAcute interstitial nephritis (AIN) is characterized by an inflammatory infiltrate in the renal interstitium. The etiology of AIN is broad...
-
Role of natural secondary metabolites as HIF-1 inhibitors in cancer therapy
Hypoxia-inducible Factor 1 (HIF-1) is a transcriptional activator that intervenes in versatile reactions to hypoxia. Natural drugs, widely...
-
A case report involving suppressed nuclear receptor transcription factors 4a1 and Stevens-Johnson syndrome induced by a single dose of pembrolizumab and successfully treated with early steroid administration, resulting in complete remission of stage III lung cancer
BackgroundImmunotherapy with immune checkpoint inhibitors is associated with immune-related adverse events (irAEs). A positive correlation between...
-
Novel Immunosuppression in Solid Organ Transplantation
Solid organ transplantation and survival has improved tremendously in the last few decades, much of the success has been attributed to the...
-
Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids
BackgroundSex steroid hormone receptors are classified into three classes of receptors: estrogen receptors (ER) α and β, androgen receptor (AR), and...
-
Therapeutic effects of dexamethasone-loaded hyaluronan nanogels in the experimental cholestasis
A major function of the intrahepatic biliary epithelium is bicarbonate excretion in bile. Recent reports indicate that budesonide, a corticosteroid...
-
Pharmacometabolomics of Asthma as a Road Map to Precision Medicine
Pharmacometabolomics applies the principles of metabolomics to therapeutics in order to elucidate the biological mechanisms underlying the variation...
-
Phytochemical analysis, physicochemical, pharmacokinetic properties and molecular docking studies of bioactive compounds in Ottelia alismoides (L.) pers. Against breast cancer proteins
Plants provide compounds that can be used to treat diseases, and in silico methods help to expedite drug discovery while reducing costs. This study...
-
Effect of Stanozolol and/or Cannabis Abuse on Hypertrophic Mechanism and Oxidative Stress of Male Albino Rat Cardiac Tissue in Relation to Exercise: A Sport Abuse Practice
Adolescents commonly co-abuse many drugs including anabolic androgenic steroids either they are athletes or non-athletes. Stanozolol is the major...
-
Roger A. Gorski
Roger A. Gorski was a neuroendocrinologist who helped shape the understanding of the role of sex steroid hormonesSex steroid hormones in the...
-
Modulators of ROS/NF-κB Signaling in Cancer Therapy
Oxidative stress regulates NF-κB signaling pathway and induces the transcription of genes related to apoptosis and cell proliferation. Due to its...
-
Concentrations of estradiol, progesterone and testosterone in serum and cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage correlate weakly with transcranial Doppler flow velocities
BackgroundThe implication of the steroids estradiol, progesterone and testosterone in cerebral vasospasm after aneurysmal subarachnoid hemorrhage...
-
Biological Activities of Some Edible Mushrooms
Since ancient times, mushrooms have been a valuable food source and traditional medicine worldwide. Edible mushrooms possess high nutritional value...
-
An evaluation of the antioxidant capacities of Dillenia excelsa extracts and its wound healing activity in Wistar rats
Dillenia excelsa , a medicinal plant found in Brunei Darussalam, has been traditionally used by locals for treating various ailments. The present...
-
Clinical Features and Genetic Analysis of Taiwanese Primary Immunodeficiency Patients with Prolonged Diarrhea and Monogenetic Inflammatory Bowel Disease
PurposeDiarrhea lasting longer than 14 days which fails to respond to conventional management is defined as severe and protracted diarrhea and might...
