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Homeostatic sleep regulation in the absence of the circadian sleep‐regulating component: effect of short light–dark cycles on sleep–wake stages and slow waves
BackgroundAside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation....
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Changes in Resting-State Neural Activity and Nerve Fibres in Ischaemic Stroke Patients with Hemiplegia
Many neuroimaging studies have reported that stroke induces abnormal brain activity. However, little is known about resting-state networks (RSNs) and...
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Volumetric Imaging of Neural Activity by Light Field Microscopy
Recording the highly diverse and dynamic activities in large populations of neurons in behaving animals is crucial for a better understanding of how...
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Reduction and recovery of self-sustained muscle activity after fatiguing plantar flexor contractions
PurposePersistent inward calcium and sodium currents (PICs) are crucial for initiation and maintenance of motoneuron firing, and thus muscular force....
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Disentangling the impact of cerebrospinal fluid formation and neuronal activity on solute clearance from the brain
BackgroundDespite recent attention, pathways and mechanisms of fluid transposition in the brain are still a matter of intense discussion and driving...
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Regional White Matter Atrophy Correlates with Spike Activity in Encephalopathy Related to Status Epilepticus During Slow Sleep (ESES) After Early Thalamic Lesions
Encephalopathy related to Status Epilepticus during slow Sleep (ESES) is an age-related, epileptic syndrome, which associates cognitive/behavioral...
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Hippocampal oscillatory dynamics in freely behaving rats during exploration of social and non-social stimuli
Hippocampal CA2 supports social memory and encodes information about social experiences. Our previous study showed that CA2 place cells responded...
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Effects of Sleep Deprivation and Experience on Sleep Characteristics and Memory Formation Based on EEG Analysis
Sleep is believed to play an important role in cognitive functions. The underlying mechanisms of the relationship between the effects of waking... -
Sleep restores an optimal computational regime in cortical networks
Sleep is assumed to subserve homeostatic processes in the brain; however, the set point around which sleep tunes circuit computations is unknown....
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Participation of Modulating Rhythms of the Decasecond Range in Intersystem Correlation Interactions in Early Rat Ontogeny
On newborn non-narcotized 1-day-old (P1) and 16-day-old (P16) rats, a detailed analysis of intersystem somatovisceral interactions (ISI) mediated by...
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Contingent Negative Variation (CNV)
The contingent negative variation (CNV), first described by Gray Walter in 1964 as “expectancy wave,” is a slow cortical endogenous potential widely... -
Comparison of Dry and Wet Electrodes for Detecting Gastrointestinal Activity Patterns from Body Surface Electrical Recordings
Gastrointestinal motility patterns can be mapped via electrical signals measured non-invasively on the body surface. However, short-term (≈ 2–4 h)...
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Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer’s disease model
BackgroundAlzheimer’s disease (AD) patients exhibit memory disruptions and profound sleep disturbances, including disruption of deep non-rapid eye...
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Cortical Up-States as a General Leitmotif
We have discussed above the slow oscillation of sleep and some of its physiological properties, particularly including its robustness and the... -
Intra-host mutation rate of acute SARS-CoV-2 infection during the initial pandemic wave
SARS-CoV-2 mutation is minimized through a proofreading function encoded by NSP-14 . Most estimates of the SARS-CoV-2 mutation rate are derived from...
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How Much Time to Spend in Physical Activity, Sleep and be Sedentary in 24 h to Achieve Good Health?
One should have adequate amount of good quality sleep on a regular and consistent basis on weekdays and weekends along with adequate amount of...
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Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making
Understanding how cortical circuits generate complex behavior requires investigating the cell types that comprise them. Functional differences across...
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Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans
Memory consolidation during sleep is thought to depend on the coordinated interplay between cortical slow waves, thalamocortical sleep spindles and...