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Direct association with the vascular basement membrane is a frequent feature of myelinating oligodendrocytes in the neocortex
BackgroundOligodendrocyte lineage cells interact with the vasculature in the gray matter. Physical and functional interactions between blood vessels...
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Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs
The purinergic system is one of the oldest cell-to-cell communication mechanisms and exhibits relevant functions in the regulation of the central...
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A Fiber Dissection Study of the Anterior Commissure: Correlations with Diffusion Spectrum Imaging Tractography and Clinical Relevance in Gliomas
The anterior commissure, which connects bilateral temporal lobes and olfactive areas, remains elusive in many aspects of its structure and functional...
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Quail-chick grafting experiments corroborate that Tbr1-positive eminential prethalamic neurons migrate along three streams into hypothalamus, subpallium and septocommissural areas
The prethalamic eminence (PThE), a diencephalic caudal neighbor of the telencephalon and alar hypothalamus, is frequently described in mammals and...
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A new map of the rat isocortex and proisocortex: cytoarchitecture and M2 receptor distribution patterns
Neurotransmitters and their receptors are key molecules in information transfer between neurons, thus enabling inter-areal communication. Therefore,...
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Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer’s Disease Mouse Models
Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a class B G protein-coupled receptor (GPCR), is a potential modulator...
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Disrupted white matter functional connectivity in aMCI APOEε4 carriers: a resting-state study
The ε4 allele of the APOE gene is thought to increase risk from amnestic mild cognitive impairment (aMCI) to Alzheimer’s disease. Cognitive decline...
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A radial histogenetic model of the mouse pallial amygdala
Conventional anatomic models of the rodent (mammalian) amygdala are based on section planes oblique to its intrinsic radial glial organization. As a...
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Neuroimaging and immunological features of neurocognitive function related to substance use in people with HIV
This study sought to identify neuroimaging and immunological factors associated with substance use and that contribute to neurocognitive impairment...
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A Potential Role for Neuroinflammation in ADHD
Attention deficit hyperactivity disorder (ADHD) is a neurobehavioural disorder in children and adolescents. Although increases in oxidative stress... -
Preparation of Rat Organotypic Hippocampal Slice Cultures Using the Membrane-Interface Method
Cultured hippocampal slices from rodents, in which the architecture and functional properties of the hippocampal network are largely preserved, have... -
Commentary on “The Significance of the Granular Layer of the Cerebellum: a Communication by Heinrich Obersteiner (1847–1922) Before the 81st Meeting of the Society of German Natural Scientists and Physicians in Salzburg, September 1909”
This commentary highlights a “cerebellar classic” by Heinrich Obersteiner (1847–1922), the founder of Vienna’s Neurological Institute. Obersteiner...
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Association between human gray matter metabotropic glutamate receptor-5 availability in vivo and white matter properties: a [11C]ABP688 PET and diffusion tensor imaging study
Excitatory corticofugal projections in the subcortical white matter (WM) convey signals arising from local neuronal activity in the gray matter (GM)....
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Tracing in vivo the dorsal loop of the optic radiation: convergent perspectives from tractography and electrophysiology compared to a neuroanatomical ground truth
The temporo-parietal junction (TPJ) is a cortical area contributing to a multiplicity of visual, language-related, and cognitive functions. In line...
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The Effects of Neuropathic Pain on the State of Glial Cells and Hippocampal Neurogenesis in Old Animals
Abstract —We studied the effect of chronic neuropathic pain on the state of microglia and neurogenesis in the hippocampus in old mice. Neuropathic...
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Lipid-accumulated reactive astrocytes promote disease progression in epilepsy
Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we...
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Investigating the Impact of Intracerebroventricular Streptozotocin on Female Rats with and without Ovaries: Implications for Alzheimer’s Disease
To contribute to research on female models of Alzheimer’s disease (AD), our aim was to study the effect of intracerebroventricular (ICV) injection of...
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Support vector machine based classification of smokers and nonsmokers using diffusion tensor imaging
Despite significant progress in treatments for smoking cessation, smoking continues to be a significant public health concern, especially in young...
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Influence of Pain on Cognitive Dysfunction and Emotion Dysregulation in Chiari Malformation Type I
It has been well demonstrated that the cerebellum is associated with cognitive and affective processing as well as the traditionally conceptualized... -
Exendin-4 Prevents Memory Loss and Neuronal Death in Rats with Sporadic Alzheimer-Like Disease
This study investigated the neuroprotective effects of exendin-4 (EXE-4), an analog of the glucagon-like peptide 1 receptor (GLP-1R) on memory and on...