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The Role of Early Life Programming in Vulnerability and Resilience in Relation to HIV
The pathogenesis of human immunodeficiency virus (HIV)-1 infection has a variable progression rate. Although some individuals progress rapidly to...
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10th Anniversary of the European Association for Predictive, Preventive and Personalised (3P) Medicine - EPMA World Congress Supplement 2020
In 2019, the EPMA celebrated its 10th anniversary at the 5th World Congress in Pilsen, Czech Republic. The history of the International Professional...
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Magnetic Resonance Spectroscopy in Schizophrenia: Evidence for Glutamatergic Dysfunction and Impaired Energy Metabolism
In the past couple of decades, major efforts were made to increase reliability of metabolic assessments by magnetic resonance methods. Magnetic...
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Depressive States at the Stage of Manifest Clinical Signs of Anorexia Nervosa in Adolescents
Study aims. To describe the psychopathological characteristics and dynamics of depression develo** at the stage of manifest clinical signs of...
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Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with high heritability rates. The contribution of genetic factors...
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The Biosocial Bases of Aggressivity and Aggressive Behavior
This review provides a brief exposition of the biosocial bases of the formation and expression of aggressivity in human society. The main watershed...
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Mother–infant interactions and regional brain volumes in infancy: an MRI study
It is generally agreed that the human brain is responsive to environmental influences, and that the male brain may be particularly sensitive to early...
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Blunted neuroactive steroid and HPA axis responses to stress are associated with reduced sleep quality and negative affect in pregnancy: a pilot study
RationaleAnxiety during pregnancy has been linked to adverse maternal health outcomes, including postpartum depression (PPD). However, there has been...
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Global white matter microstructural abnormalities associated with addiction liability score in drug naïve youth
Abnormalities in brain white matter (WM) structure have been reported in youths having a family history of substance use disorders (SUDs). It was...
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Perinatal Programming Prevention Measures
Over the past 10 years, there has been outstanding scientific progress related to perinatal programming and its epigenetic effects in health, and we...
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Chromosomal microarray testing in adults with intellectual disability presenting with comorbid psychiatric disorders
Chromosomal copy-number variations (CNVs) are a class of genetic variants highly implicated in the aetiology of neurodevelopmental disorders,...
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Impact of the Perinatal Environment on the Child’s Development: Implications for Prevention Policies
Basic emotional security is central to the construction of the child and has an impact on the brain’s organisation, the personal...
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A New Method for the Treatment of Korsakoff’s (amnestic) Psychosis: Neurostimulation Correction of the Sympathetic Nervous System
Objective. Using data on the evolution of electrical brain stimulation and considering the pathophysiological aspect of neurostimulation correction...
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The Role of the Microbiome in the Relationship of Asthma and Affective Disorders
The effect of stress, anxiety and other affective states on inflammatory conditions such as asthma is well documented. Although several immune...
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The Management of Bipolar Disorder During and After Pregnancy
This chapter will discuss the issues of psychiatric management of bipolar disorder (BD) both during and after pregnancy. The risks and benefits of...
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From Vulnerability to Neurotoxicity: A Developmental Approach to the Effects of Stress on the Brain and Behavior
Many studies published over the last two decades show that chronic exposure to stress hormones, from the prenatal to aging period, can have...