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1. Deregulation of NF-κB associated long non-coding RNAs in bipolar disorder

   Long non-coding RNAs (lncRNAs) are major genetic factors whose disruption lead to many diseases, including nervous system diseases. Bipolar disorder...

   Razieh Ghasemi Pirbalouti, Mahdieh Mehrab Mohseni, ... Zeinab Shirvani-Farsani in Metabolic Brain Disease

   Article 06 June 2023
   

2. Identification of Novel Prognostic Long Non-coding RNAs in Lung Adenocarcinoma Using WGCNA Analysis

   Long non-coding RNAs play crucial role in the tumorigenesis of lung adenocarcinoma (LUAD). However, the function of a large number of lncRNAs in LUAD...

   Can Zhao, Han Xu, Chang Liu in Biochemical Genetics

   Article 16 June 2023
   

3. Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

   Background

   Diabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero...

   Line Hjort, Sandra Stokholm Bredgaard, ... Louise Torp Dalgaard in Clinical Epigenetics

   Article Open access 07 May 2024
   

4. Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases

   Background

   Whole genome sequencing is increasingly being used for the diagnosis of patients with rare diseases. However, the diagnostic yields of many...

   Alistair T. Pagnamenta, Carme Camps, ... Jenny C. Taylor in Genome Medicine

   Article Open access 09 November 2023
   

5. Long non-coding RNAs regulate fatty acid and cholesterol metabolism

   In recent years, long non-coding RNAs (lncRNAs) have emerged as critical players in regulating biological processes at various levels. LncRNAs...

   Kai Lei, Lei Qu, ... Aifu Lin in Genome Instability & Disease

   Article 17 March 2022
   

6. Recommendations for clinical interpretation of variants found in non-coding regions of the genome

   Background

   The majority of clinical genetic testing focuses almost exclusively on regions of the genome that directly encode proteins. The important...

   Jamie M. Ellingford, Joo Wook Ahn, ... Nicola Whiffin in Genome Medicine

   Article Open access 19 July 2022
   

7. The Mechanisms of Long Non-coding RNA-XIST in Ischemic Stroke: Insights into Functional Roles and Therapeutic Potential

   Ischemic stroke, which occurs due to the occlusion of cerebral arteries, is a common type of stroke. Recent research has highlighted the important...

   Maryam Farzaneh, Omid Anbiyaee, ... Sajad Najafi in Molecular Neurobiology

   Article 06 November 2023
   

8. Cellular Senescence-Related Long Non-coding RNA Signatures Predict Prognosis in Juvenile Osteosarcoma

   Osteosarcoma is the most common malignant bone tumor and is frequently diagnosed in juvenile. Cellular senescence is a fundamental hallmark of...

   Peng Zhao, Junli Chang, ... Yan** Yang in Phenomics

   Article Open access 08 July 2024
   

9. The emerging roles of long non-coding RNA (lncRNA) H19 in gynecologic cancers

   Long non-coding RNA (lncRNA) H19 has gained significant recognition as a pivotal contributor to the initiation and advancement of gynecologic...

   Majid Ghasemian, Mojtaba Zehtabi, ... Maryam Farzaneh in BMC Cancer

   Article Open access 02 January 2024
   

10. Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders

    HOX transcript antisense intergenic RNA ( HOTAIR ) is a long non-coding RNA (lncRNA) which is increasingly being perceived as a tremendous molecular...

    Faraz Ahmad, Ravi Sudesh, ... Shafiul Haque in Cellular and Molecular Neurobiology

    Article Open access 16 February 2024
    

11. Expression of Pivotal Long Non-coding RNAs Implicated in Gastric Cancer: A Bioinformatic and Clinical Study

    Gastric cancer (GC) is a prominent public health issue and ranks as the third most prevalent cause of cancer-related mortality on a global scale. The...

    Ramtin Mohammadi, Ali Zareh, ... Mohammad Heiat in Biochemical Genetics

    Article 09 December 2023
    

12. Long non-coding RNA ACTA2-AS1 suppresses metastasis of papillary thyroid cancer via regulation of miR-4428/KLF9 axis

    Background

    Metastasis is the primary cause of recurrence and death in patients with papillary thyroid carcinoma (PTC). LncRNA ACTA2-AS1, a long...

    Shuhui Wu, **g**g Zhu, ... **ang Chen in Clinical Epigenetics

    Article Open access 09 January 2024
    

13. Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme

    Glioblastoma Multiforme (GBM) is the primary brain tumor and accounts for 200,000 deaths each year worldwide. The standard therapy includes surgical...

    Janaki Ramaiah Mekala, Kowsalya Adusumilli, ... Hari Sai Ram Angirekula in Metabolic Brain Disease

    Article 30 May 2023
    

14. Exosomal Non-coding RNAs

    Cancer remains to be one of the major cause of morbidity and mortality worldwide with breast cancer being the most frequently diagnosed cancer among...

    Rajalakshmi Prakash, Kaumudi Pande, Anbarasu Kannan in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

    Reference work entry 2022
    

15. Exosomal Non-coding RNAs

    Cancer remains to be one of the major cause of morbidity and mortality worldwide with breast cancer being the most frequently diagnosed cancer among...

    Rajalakshmi Prakash, Kaumudi Pande, Anbarasu Kannan in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

    Living reference work entry 2022
    

16. Construction of a Prognostic Risk Prediction Model Based on m6A-Associated Long Non-Coding RNAs in Cholangiocarcinoma

    Abstract

    To screen long non-coding RNAs (lncRNAs) associated with the N6-methyladenosine (m6A) gene and create a prognostic risk model for...

    Y. Dai, S. Zhang, ... Q. He in Russian Journal of Genetics

    Article 21 May 2024
    

17. Long non-coding RNA LINC00930 targeting miR-6792-3p/ZBTB16 regulates the proliferation and EMT of pancreatic cancer

    Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930...

    Yingqing Mao, **an Su, ... Yuhua Lu in BMC Cancer

    Article Open access 24 May 2024
    

18. Pollutant-Induced DNA Damage

    The presence of pollutants in our environment has become a significant concern for human health and well-being. Numerous studies have shown a strong...

    Kimia Kazemzadeh, Alireza Zali in Handbook of Cancer and Immunology

    Living reference work entry 2024
    

19. Hypermethylation of Long Non-Coding RNA Genes Group in the Breast Cancer Development and Progression

    We analyzed changes in the level of methylation of CpG islands in four long non-coding RNA (lncRNA) genes MEG3 , ZNF667-AS1 , GAS5 , and SEMA3B-AS1 as...

    A. D. Selezneva, E. A. Filippova, ... V. I. Loginov in Bulletin of Experimental Biology and Medicine

    Article 01 October 2022

20. Long non-coding RNAs: novel regulators of cellular physiology and function

    Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA transcription. They are now understood to play central roles in...

    James A. Oo, Ralf P. Brandes, Matthias S. Leisegang in Pflügers Archiv - European Journal of Physiology

    Article Open access 18 November 2021