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The independence of impairments in proprioception and visuomotor adaptation after stroke
BackgroundProprioceptive impairments are common after stroke and are associated with worse motor recovery and poor rehabilitation outcomes. Motor...
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Genotoxicity of methyl acrylate and ethyl acrylate and its relationship with glutathione
Methyl acrylate (MA) and ethyl acrylate (EA) had previously tested positive for mutagenicity in vitro, but in vivo studies were negative. One of the...
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The History of the Loa loa Parasite, Its Biology and Experimental Models
Loiasis affects an estimated population of 14.4 million people living in rainforest areas of West and Central Africa. Although the disease is known...
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Special Populations: Profiling the Effect of Obesity on Drug Disposition and Pharmacodynamics
The health implications of obesity remain a global issue with approximately 13% of the world’s population categorized as obese (body mass index [BMI]...
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Hemodynamic and neuromuscular basis of reduced exercise capacity in patients with end-stage renal disease
PurposeThe present study aimed to characterize the exercise-induced neuromuscular fatigue and its possible links with cerebral and muscular oxygen...
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Predictive value of common genetic variants in idiopathic pulmonary fibrosis survival
AbstractIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial pneumonia of unknown etiology. The role of genetic risk...
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OME-Zarr: a cloud-optimized bioimaging file format with international community support
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity....
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miRNA Theranostic Nanoparticles Promote Pancreatic Beta Cell Proliferation in Type 1 Diabetes Model
Type 1 diabetes (T1D) is a chronic autoimmune disorder which affects the insulin-producing beta cells in the pancreas. A variety of strategies,...
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Association of HIV serostatus and metabolic syndrome with neurobehavioral disturbances
Metabolic syndrome (MetS), a constellation of related metabolic risk factors, is a common comorbidity associated with cognitive difficulty in people...
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Antisense Oligonucleotide Therapy Against SCA3
Spinocerebellar ataxia type 3 (SCA3), also known as Machado Joseph disease, is a dominantly inherited neurodegenerative disease that has remained, to...
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Biological relevance of alternative splicing in hematologic malignancies
Alternative splicing (AS) is a strictly regulated process that generates multiple mRNA variants from a single gene, thus contributing to proteome...
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Zika Virus Studies in West Africa
Several of the most important human arboviral pathogens, including yellow fever, chikungunya, and Zika viruses, originated in enzootic African...
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Emergence of CWD strains
Chronic wasting disease (CWD) strains present a novel challenge to defining and mitigating this contagious prion disease of deer, elk, moose, and...
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Ring Chromosome 6
Ring chromosome 6 (RC6) is a rare constitutional structural abnormality that generally occurs during meiosis or early post-zygotic mitosis. Most of...
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Genetic, maternal, and environmental influences on sociality in a pedigreed primate population
Various aspects of sociality in mammals (e.g., dyadic connectedness) are linked with measures of biological fitness (e.g., longevity). How within-...
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Human Babesia odocoilei and Bartonella spp. co-infections in the Americas
BackgroundIn recent years, Babesia and Bartonella species co-infections in patients with chronic, nonspecific illnesses have continued to challenge...
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Welcome to the 2024 ACMT Annual Scientific Meeting
Two hundred sixteen abstracts were selected for presentation at the 2024 American College of Medical Toxicology (ACMT) Annual Scientific Meeting on...
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An alternative approach of TUNEL assay to specifically characterize DNA fragmentation in cell model systems
DNA damage is one of the most important effects induced by chemical agents. We report a comparative analysis of DNA fragmentation on three different...
