Search
Search Results
-
The crosstalk between reactive oxygen species and noncoding RNAs: from cancer code to drug role
Oxidative stress (OS), characterized by the excessive accumulation of reactive oxygen species (ROS), is an emerging hallmark of cancer. Tumorigenesis...
-
Metformin and long non-coding RNAs in breast cancer
Breast cancer (BC) is the second most common cancer and cause of death in women. In recent years many studies investigated the association of long...
-
Activity of Genes and Noncoding RNAs as an Approach to Determination of Early Biomarkers of Radiation-Induced Cancer in Mice
AbstractThe activity of genes and noncoding RNAs was studied in 183 hybrid mice (CBA × C57Bl) F 1 after a prolonged low-power irradiation (within 21...
-
Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma
BackgroundLong noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and play fundamental roles in various types of cancer....
-
H3K27 acetylation activated long noncoding RNA RP11-162G10.5 promotes breast cancer progression via the YBX1/GLO1 axis
PurposeLong noncoding RNAs (lncRNAs) orchestrate critical roles in human tumorigenesis. However, the regulatory mechanism of lncRNAs in...
-
The chromatin-associated RNAs in gene regulation and cancer
Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into proteins or execute gene regulatory functions. Many RNAs...
-
Spatial transcriptome analysis of long non-coding RNAs reveals tissue specificity and functional roles in cancer
Long non-coding RNAs (lncRNAs) play a significant role in maintaining tissue morphology and functions, and their precise regulatory effectiveness is...
-
Long Noncoding RNA Acting as Therapeutic Target for Oxidative Stress-Induced Pancreatic Cancer
Pancreatic cancer (PanCa) is a systemic disease with both locally advanced and malignant neoplastic phenotypes and has a poor prognosis. Among all...
-
Long Noncoding RNA Acting as Therapeutic Target for Oxidative Stress-Induced Pancreatic Cancer
Pancreatic cancer (PanCa) is a systemic disease with both locally advanced and malignant neoplastic phenotypes and has a poor prognosis. Among all...
-
Circular RNAs in renal cell carcinoma: from mechanistic to clinical perspective
CircRNAs, a special type of noncoding RNAs characterized by their stable structure and unique abilities to form backsplicing loops, have recently...
-
Functional interplay between long non-coding RNAs and Breast CSCs
Breast cancer (BC) represents aggressive cancer affecting most women’s lives globally. Metastasis and recurrence are the two most common factors in a...
-
Long non-coding RNAs in biomarking COVID-19: a machine learning-based approach
BackgroundThe coronavirus pandemic that started in 2019 has caused the highest mortality and morbidity rates worldwide. Data on the role of long...
-
Long noncoding RNAs as tumorigenic factors and therapeutic targets for renal cell carcinoma
Approximately 338,000 patients are diagnosed with kidney cancer worldwide each year, and renal cell carcinoma (RCC), which is derived from renal...
-
Hotair and Malat1 Long Noncoding RNAs Regulate Bdnf Expression and Oligodendrocyte Precursor Cell Differentiation
Brain-derived neurotrophic factor (BDNF ) is a member of the neurotrophins family with well-known roles in neural development, differentiation,...
-
Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications
Exosomes are a subpopulation of the tumour microenvironment (TME) that transmit various biological molecules to promote intercellular communication....
-
Noncoding RNAs regulate alternative splicing in Cancer
AS (alternative splicing) is a fundamental process by which a gene can generate multiple distinct mRNA transcripts to increase protein diversity....
-
Mouse as a Preclinical Model for Studying Small Noncoding RNAs Involved in Colorectal Cancer
Colorectal cancer (CRC) is the third most diagnosed cancer and occupies the second position in death among other cancer deaths in both sexes due to...
-
Knockdown of Long Noncoding RNA CCAT2 Suppresses Malignant Phenotype in Human Laryngeal Squamous Cell Carcinoma
This study aimed to explore the biological role and mechanism underlying the effects of colon cancer-associated transcript 2 ( CCAT2 ), a long...
-
The Long Noncoding RNA Gall Bladder Cancer-Associated Suppressor of Pyruvate Carboxylase Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer Cells and Induces Their Apoptosis
This study aimed to determine the role of the long noncoding RNA (lncRNA) gall bladder cancer-associated suppressor of pyruvate carboxylase (SOD2-1)...
-
Hypermethylation in Ovarian Cancer of Long Noncoding RNA Genes: HOTAIR, GAS5, LINC00472, LINC00886, TUG1
AbstractRecently, more and more data have been accumulating indicating the role of long noncoding RNAs (lncRNAs) in the regulation of biological...
