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Current Approaches and Methods to Understand Acute Ischemic Stroke Treatment Using Aspiration Thrombectomy
Acute ischemic stroke occurs when a blood clot occludes a cerebral artery. Mechanical interventions, primarily stent retrievers and aspiration...
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On Distributed Visual Systems
Many vision scientists have been drawn to study the remarkable diversity of animal eyes, ranging from very simple light sensors to highly...
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Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes
Diabetes-associated cognitive dysfunction (DACD) is considered a significant complication of diabetes and manifests as cognitive impairment....
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Prospects for online adaptive radiation therapy (ART) for head and neck cancer
BackgroundThe aim of the present study is to examine the impact of kV-CBCT-based online adaptive radiation therapy (ART) on dosimetric parameters in...
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Restricted truncal sagittal movements of rapid eye movement behaviour disorder
Unlike sleep-walkers, patients with rapid-eye-movement-behaviour disorder (RBD) rarely leave the bed during the re-enactment of their dreams. RBD...
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MRI-guided robot intervention—current state-of-the-art and new challenges
Magnetic Resonance Imaging (MRI) is now a widely used modality for providing multimodal, high-quality soft tissue contrast images with good...
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HDAC6 modulates the cognitive behavioral function and hippocampal tissue pathological changes of APP/PS1 transgenic mice through HSP90-HSF1 pathway
The aim of this study was to investigate histone deacetylase 6 (HDAC6) modifies the heat shock protein 90 (HSP90) and heat shock transcription factor...
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SS-31 inhibits mtDNA–cGAS–STING signaling to improve POCD by activating mitophagy in aged mice
BackgroundNeuroinflammation is crucial in the development of postoperative cognitive dysfunction (POCD), and microglial activation is an active...
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Homing tasks and distance matching tasks reveal different types of perceptual variables associated with perceiving self-motion during over-ground locomotion
Self-motion perception refers to the ability to perceive how the body is moving through the environment. Perception of self-motion has been shown to...
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Evaluation of the Spanish-Language Cancer Educational Webinar Series “Vamos a educarnos contra el cáncer” with the RE-AIM Framework
The COVID-19 pandemic disrupted healthcare for patients with chronic diseases, including cancer. Barriers to healthcare increased, especially for...
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Multivariate investigation of aging in mouse models expressing the Alzheimer’s protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
APOE allelic variation is critical in brain aging and Alzheimer’s disease (AD). The APOE2 allele associated with cognitive resilience and...
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Electroacupuncture improves cognitive impairment in diabetic cognitive dysfunction rats by regulating the mitochondrial autophagy pathway
BackgroundDiabetes-associated cognitive dysfunction has become a major public health concern. However, the mechanisms driving this disease are...
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Cornuside ameliorates cognitive impairments via RAGE/TXNIP/NF-κB signaling in Aβ1-42 induced Alzheimer’s disease mice
Cornuside has been discovered to improve learning and memory in AD mice, however, its underlying mechanism was not fully understood. In the present...
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Blockade of adenosine A2A receptors reverses early spatial memory defects in the APP/PS1 mouse model of Alzheimer’s disease by promoting synaptic plasticity of adult-born granule cells
BackgroundThe over-activation of adenosine A 2A receptors (A 2A R) is closely implicated in cognitive impairments of Alzheimer's disease (AD). Growing...
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Hesperetin attenuates cognitive dysfunction via SIRT6/NLRP3 pathway in scopolamine-induced mice
Neuroinflammation is a critical feature in the pathogenesis of neurodegenerative disorders such as Alzheimer’s disease (AD). Hesperetin can exert...
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A usability study on mobile EMG-guided wrist extension training in subacute stroke patients-MyoGuide
BackgroundEffective stroke rehabilitation requires high-dose, repetitive-task training, especially during the early recovery phase. However, the...
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Evaluating the usability of a co-designed power assisted exercise graphical user interface for people with stroke
BackgroundDigital advancement of power assisted exercise equipment will advance exercise prescription for people with stroke (PwS). This article...
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An eHealth symptom and complication management program for cancer patients with newly created ostomies and their caregivers (Alliance): a pilot feasibility randomized trial
BackgroundCancer patients with newly created ostomies face complications that reduce quality of life (QOL) and increase morbidity and mortality. This...
