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Biochemical recurrence in patients with prostate cancer after primary definitive therapy: treatment based on risk stratification
BackgroundNearly one-third of patients with prostate cancer (PCa) experience biochemical recurrence (BCR) after primary definitive treatment. BCR...
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Neoadjuvant Chemoradiation for Rectal Cancer Achieves Satisfactory Tumour Regression and Local Recurrence – Result of a Dedicated Multi-disciplinary Approach from a South Asian Centre
BackgroundPre-operative long-course chemoradiotherapy (CRT) for rectal cancer has resulted in improvement in rates of restorative rectal resection...
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Predicting 5-year recurrence risk in colorectal cancer: development and validation of a histology-based deep learning approach
BackgroundAccurate estimation of the long-term risk of recurrence in patients with non-metastatic colorectal cancer (CRC) is crucial for clinical...
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Clinical determinants of recurrence in pTa bladder cancer following transurethral resection of bladder tumor
BackgroundNon-muscle invasive bladder cancer can be controlled by transurethral resection of bladder (TURB), but suffers from frequent recurrences in...
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Hypermethylated TAGMe as a universal-cancer-only methylation marker and its application in diagnosis and recurrence monitoring of urothelial carcinoma
BackgroundUrothelial carcinoma (UC) is the second most common urological malignancy. Despite numerous molecular markers have been evaluated during...
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Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer
Locoregional recurrences represent a frequently unexpected problem in head and neck squamous cell carcinoma (HNSCC). Relapse often (10–30%) occurs in...
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Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
BackgroundCurrent risk models in solitary fibrous tumour (SFT) were developed using cohorts with short follow-up and cannot reliably identify...
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Transcriptomics-based liquid biopsy panel for early non-invasive identification of peritoneal recurrence and micrometastasis in locally advanced gastric cancer
BackgroundThis study aimed to develop a novel six-gene expression biomarker panel to enhance the early detection and risk stratification of...
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Recurrence and survival of patients with stage III endometrial cancer after radical surgery followed by adjuvant chemo- or chemoradiotherapy: a systematic review and meta-analysis
ObjectiveTo compare recurrence and survival in patients with stage III endometrial cancer after radical surgery, followed by either adjuvant...
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The Drainage Dysfunction of Meningeal Lymphatic Vessels Is Correlated with the Recurrence of Chronic Subdural Hematoma: a Prospective Study
Meningeal lymphatic vessels (mLVs) were recently discovered to be involved in the waste drainage process in the brain, which has also been associated...
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A liquid biopsy signature for predicting early recurrence in patients with gastric cancer
BackgroundGastric cancer (GC) patients who experience recurrence within the first year following surgery (early recurrence [ER]) exhibit worse...
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Antidepressant medication use and prostate cancer recurrence in men with depressive disorders
PurposeWhether treating prostate cancer survivors with a depressive disorder with antidepressants can affect their cancer outcomes is unknown. We...
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Risk stratification of lateral neck recurrence for patients with pN1a papillary thyroid cancer
BackgroundLateral neck is not recommended for dissection in patients with pN1a papillary thyroid cancer (PTC), but its recurrence risk has not been...
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Development and validation of postoperative circulating tumor DNA combined with clinicopathological risk factors for recurrence prediction in patients with stage I-III colorectal cancer
BackgroundCirculating tumor DNA (ctDNA) detection following curative-intent surgery could directly reflect the presence of minimal residual disease,...
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Postdiagnosis circulating osteoprotegerin and TRAIL concentrations and survival and recurrence after a breast cancer diagnosis: results from the MARIE patient cohort
BackgroundExperimental studies suggest a role for osteoprotegerin (OPG) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in...
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Breast Cancer Recurrence and Survival
Recurrence of breast cancer is a major cause of the disease-specific death. In general, it occurs within 5 years or even up to 10–20 years after... -
The role of adjuvant transcatheter arterial chemoembolization following repeated curative resection/ablation for hepatocellular carcinoma with early recurrence: a propensity score matching analysis
BackgroundThe role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular...
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Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia
BackgroundOral epithelial dysplasia (OED) is the precursor to oral squamous cell carcinoma which is amongst the top ten cancers worldwide. Prognostic...
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Prognostic factors associated with early recurrence following liver resection for colorectal liver metastases: a systematic review and meta-analysis
BackgroundColorectal cancer (CRC) is the 3rd most common malignancy with the liver being the most common site of metastases. The recurrence rate of...
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Dosimetric and clinical analysis of pseudo-progression versus recurrence after hypo-fractionated radiotherapy for brain metastases
BackgroundThe main challenge in follow-up duration of patients with brain metastases after stereotactic radiotherapy is to distinguish between...