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Imaging of Lung and Soft Tissue Metastases
Excepting our surgery and pathology colleagues, most physicians only “see” cancer via medical imaging. This evaluation is key to the diagnosis and...
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Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
ObjectiveFor patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma....
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Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma
BackgroundInvasive malignant pleomorphic adenoma (IMPA) is a highly malignant neoplasm of the oral salivary glands with a poor prognosis and a...
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Human Growth Hormone
Human growth hormone (hGH) is a protein hormone essential for normal growth and development in humans. In this chapter, the hGH structure, its...
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Undifferentiated sarcomatoid carcinoma of the pancreas-a single-institution experience with 23 cases
BackgroundThe clinical course and surgical outcomes of undifferentiated sarcomatoid carcinoma of the pancreas (USCP) remain poorly characterized...
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Understanding, diagnosing, and treating pancreatic cancer from the perspective of telomeres and telomerase
Telomerase is associated with cellular aging, and its presence limits cellular lifespan. Telomerase by preventing telomere shortening can extend the...
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Histological Variants of Papillary Thyroid Cancer in Relation to Clinical and Morphological Parameters and Prognosis
The correlation of histological features of papillary thyroid cancer with clinical and morphological prognostic factors and cause-specific mortality...
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Talniflumate abrogates mucin immune suppressive barrier improving efficacy of gemcitabine and nab-paclitaxel treatment in pancreatic cancer
BackgroundPancreatic ductal adenocarcinoma (PDAC) is a lethal disease. This is due to its aggressive course, late diagnosis and its intrinsic drugs...
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Medicinal Plant Based Advanced Drug Delivery System for the Treatment of Chronic Lung Diseases
Chronic pulmonary diseases such as bronchial asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, cystic fibrosis, and lung cancers...
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Primary Pediatric Brain Tumors of the Posterior Fossa: Part I
In pediatric neuro-oncology practice, cerebellar tumors are often referred to as infratentorial tumors or tumors of the posterior fossa (a...
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Histologic subty** affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis
BackgroundTriple Negative breast cancer (TNBC) includes a heterogeneous group of tumors with different clinico-pathological features, molecular...
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Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors
BackgroundGSK3368715, a first-in-class, reversible inhibitor of type I protein methyltransferases (PRMTs) demonstrated anticancer activity in...
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Wilms Tumor
Wilms tumor (WT) is the most common renal tumor in pediatrics, representing 6.3% of all childhood cancers. It is a developmental neoplasm that arises...
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Cancerogenic parasites in veterinary medicine: a narrative literature review
Parasite infection is one of the many environmental factors that can significantly contribute to carcinogenesis and is already known to be associated...
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Landmarks in pancreatic cancer studies
Pancreatic cancer is a rare but fatal disease. Patients present advanced disease due to the lack of or typical symptoms when the tumor is still...
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Central Nervous System Tumors
The central nervous system (CNS) is the part of the nervous system comprising the brain and the spinal cord. CNS tumors are a heterogeneous group of...
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Ultrasound of the Endocrine System
The endocrine system provides a major mechanism by which the nervous system regulates homeostasis and many body functions, including growth,...
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Clinical Aspects of the Inherited Cerebellar Malformations
Inherited cerebellar malformations cause lifelong disability and are not well studied in the newborns because there is a lack of appropriate clinical...
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Clinical Management and Surgical Decision-Making of IPMN of the Pancreas
Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cystic neoplasm (PCN). The increased attention to IPMN is due to its...
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Metastatic Lesions of the Brain and Spine
Brain and spinal metastasesMetastases are common in cancer patients and are associated with significant morbidityMorbidity and mortalityMortality....