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A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidance
PurposeHER3, a member of the EGFR receptor family, plays a central role in driving oncogenic cell proliferation in breast cancer. Novel HER3...
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Predictive Biomarkers of Response to Neoadjuvant Therapy in Muscle Invasive Bladder Cancer
Neoadjuvant cisplatin-based chemotherapy is recommended prior to surgical removal of the bladder for patients with non-metastatic muscle invasive...
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Shifting the paradigm: engaging multicellular networks for cancer therapy
Most anti-cancer modalities are designed to directly kill cancer cells deploying mechanisms of action (MOAs) centered on the presence of a precise...
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A Brief Introduction to Current Cancer Gene Therapy
Gene therapy has started in the late 1980s as novel, clinically applicable therapeutic option. It revolutionized the treatment of genetic diseases...
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Graphene-based hybrid composites for cancer diagnostic and therapy
The application of graphene-based nanocomposites for therapeutic and diagnostic reasons has advanced considerably in recent years due to advancements...
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The Intricacy of ROS in Cancer Therapy Resistance
Cancer is one of the notable causes of death universally due to the emergence of therapy resistance despite the evolution of encouraging therapeutic...
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Recent advances of engineered oncolytic viruses-based combination therapy for liver cancer
Liver cancer is a major malignant tumor, which seriously threatens human health and increases the economic burden on patients. At present, gene...
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Role of the microbiota in response to and recovery from cancer therapy
Our understanding of how the microbiota affects the balance between response to and failure of cancer treatment by modulating the tumour...
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Application of Oncolytic Poxviruses: An Emerging Paradigm in Cancer Therapy
Despite the significant advancement of new tools and technology in the field of medical biology and molecular biology, the challenges in the...
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Injectable hydrogel systems for local cancer therapy
BackgroundInjectable hydrogels have attracted significant attention for localized cancer treatment due to their tuned viscoelasticity, self-healing...
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Targeting the Metabolism in Cancer Cells for Cancer Therapy
Cellular reactive oxygen species (ROS) are a group of extremely reactive molecules and are produced by metabolic and other reduction-oxidation...
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Cancer Stem Cell Oxidative Phosphorylation: Target for Cancer Therapy
Cancer is one of the most important leading causes of death across the globe. Cancer cells that divide uncontrollably are killed by chemotherapy,...
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Nanotechnology in ROS-induced Cancer Therapy
Utilization of nanotechnology in the cancer therapy has produced nano-based products that can produce reactive oxygen species (ROS) cytotoxicity with...
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Nanotechnology in ROS-induced Cancer Therapy
Utilization of nanotechnology in the cancer therapy has produced nano-based products that can produce reactive oxygen species (ROS) cytotoxicity with...
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Targeting the Metabolism in Cancer Cells for Cancer Therapy
Cellular reactive oxygen species (ROS) are a group of extremely reactive molecules and are produced by metabolic and other reduction-oxidation...
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Cancer Stem Cell Oxidative Phosphorylation: Target for Cancer Therapy
Cancer is one of the most important leading causes of death across the globe. Cancer cells that divide uncontrollably are killed by chemotherapy,...
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Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset of tumor cells characterized by surface markers such...
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Adoptive cell transfer therapy with ex vivo primed peripheral lymphocytes in combination with anti-PDL1 therapy effectively inhibits triple-negative breast cancer growth and metastasis
BackgroundAdoptive cell transfer cancer immunotherapy holds promise for treating disseminated disease, yet generating sufficient numbers of...
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Oncological results and cancer control definition in focal therapy for Prostate Cancer: a systematic review
IntroductionFocal therapy (FT) is a promising alternative to whole-gland treatments for Localized Prostate Cancer. Ten different FT modalities have...
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Radiopharmaceuticals: A New Era in Cancer Therapy – Light on Initial Findings on Animal Model
In recent years, the worldwide cancer burden has increased dramatically. The treatment modalities for cancer are surgery, radiation therapy, and...