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Impact of the Proportion of Biopsy Positive Core in Predicting Biochemical Recurrence in Patients with Pathological Pt2 and Negative Resection Margin Status after Radical Prostatectomy
This study aimed to determine the prognostic factors associated with biochemical recurrence (BCR) after radical prostatectomy (RP) in patients with...
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Testosterone therapy does not increase the risks of prostate cancer recurrence or death after definitive treatment for localized disease
BackgroundThe safety of testosterone therapy (TT) after definitive treatment for localized prostate cancer remains undefined. We analyzed the risks...
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Relationship between Proclarix and the Aggressiveness of Prostate Cancer
IntroductionProclarix is a CE-marked test that provides the risk of clinically significant prostate cancer (csPCa), ranging from 0% to 100%, based on...
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Application of next-generation imaging in biochemically recurrent prostate cancer
BackgroundBiochemical recurrence (BCR) following primary interventional treatment occurs in approximately one-third of patients with prostate cancer...
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Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation
BackgroundEarly diagnosis can significantly improve treatment outcomes for hepatocellular carcinoma (HCC) patients. Currently, the dosage of serum...
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Differential impact of radiation therapy after radical prostatectomy on recurrence patterns: an assessment using [68Ga]Ga-PSMA ligand PET/CT(MRI)
PurposeTo evaluate the differential impact of postoperative radiotherapy (RT) on recurrence patterns in patients treated with radical prostatectomy...
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Factors associated with a SARS-CoV-2 recurrence after hospital discharge among patients with COVID-19: systematic review and meta-analysis
Background: The proportion of recurrences after discharge among patients with coronavirus disease 2019 (COVID-19) was reported to be between 9.1% and...
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Length of positive surgical margins after radical prostatectomy: Does size matter? – A systematic review and meta-analysis
ObjectivesThe prognostic capacity of positive surgical margins (PSM) for biochemical recurrence (BCR) is unclear, with inconsistent findings across...
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Establishment of a prognostic risk prediction model incorporating disulfidptosis-related lncRNA for patients with prostate cancer
PurposeProstate cancer (PCa) is one of the major tumor diseases that threaten men’s health globally, and biochemical recurrence significantly impacts...
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Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial
BackgroundMore than 60% of oligo-recurrent prostate cancer (PCa) patients treated with metastasis-directed radiotherapy (MDRT) develop biochemical...
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A DNA copy number alteration classifier as a prognostic tool for prostate cancer patients
BackgroundDistinguishing between true indolent and potentially life-threatening prostate cancer is challenging in tumours displaying...
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Introduction of salvage prostatectomy in Denmark: the initial experience
ObjectiveTo introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following...
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Impact of persistent PSA after salvage radical prostatectomy: a multicenter study
Background and objectivePersistent prostatic specific antigen (PSA) represents a poor prognostic factor for recurrence after radical prostatectomy...
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Clinical, molecular, and biochemical delineation of asparagine synthetase deficiency in Saudi cohort
PurposeAsparagine synthetase deficiency (ASNSD) is a rare neurometabolic disease. Patients may not demonstrate low asparagine levels, which...
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Transversal approach via a bladder neck and prostate combined longitudinal incision versus standard approach of robotic-assisted radical prostatectomy for localized prostate cancer: a retrospective analysis
BackgroundTransversal approach for robotic-assisted radical prostatectomy via a bladder neck and prostate combined longitudinal incision (L-RALP) is...
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SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy
BackgroundProstate cancer (PC) is a commonly diagnosed malignancy in males, especially in the western hemisphere. The extensive use of multiple...
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Oncological outcomes of cribriform histology pattern in prostate cancer patients: a systematic review and meta-analysis
BackgroundChanges applied to the Prostate cancer (PCa) histopathology grading, where patients with cribriform patterns (CP) may be categorized as...
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Histopathological and Molecular Markers in the Assessment of Prostate Cancer Aggressivity
Prostate cancer (PCa) in most patients does not cause significant clinical symptoms, but high-risk disease, accounting for approximately 15% of PCa,... -
Diagnostic value of multiparametric MRI in detecting residual or recurrent prostate cancer after high-intensity focused ultrasound
PurposeTo evaluate the diagnostic performance of follow-up multiparametric MRI for prediction of recurrent prostate cancer after high-intensity...
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Sphingomyelin(d35:1) as a novel predictor for lung adenocarcinoma recurrence after a radical surgery: a case-control study
BackgroundTo improve the postoperative prognosis of patients with lung cancer, predicting the recurrence high-risk patients is needed for the...