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Liraglutide attenuates palmitate-induced apoptosis via PKA/β-catenin/Bcl-2/Bax pathway in MC3T3-E1 cells
Liraglutide (LRG), one agonist of glucagon-like peptide-1 receptor (GLP1R), has multiple lipid-lowering effects in type 2 diabetes mellitus, however,...
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Enniatins from a marine-derived fungus Fusarium sp. inhibit biofilm formation by the pathogenic fungus Candida albicans
Candidemia is a life-threatening disease common in immunocompromised patients, and is generally caused by the pathogenic fungus Candida albicans . C....
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Molecular characterization of enterovirus detected in cerebrospinal fluid and wastewater samples in Monastir, Tunisia, 2014–2017
BackgroundEnteroviruses (EVs) are considered the main causative agents responsible for aseptic meningitis worldwide. This study was conducted in the...
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Barriers and facilitators for the implementation of patient-centered care in cardiogenetics: a Delphi study among ERN GUARD-heart members
Current clinical practice regarding inherited cardiac conditions has a biomedical focus, while psychological and social expertize and capacity are...
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Genetic association of PRKCD and CARD9 polymorphisms with Vogt–Koyanagi–Harada disease in the Chinese Han population
BackgroundProtein kinase C delta ( PRKCD ) and caspase recruitment domain family member 9 ( CARD9 ) are genes involved in B and T cell activation, and...
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Mitochondrial Dysfunction Contributes To Zinc-induced Neurodegeneration: a Link with NADPH Oxidase
Mitochondrial dysfunction and nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) are the major sources of augmentation in free...
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Food XenomiRNA Arise: MicroRNA Storm and Space
MicroRNAs (miRNAs) are mobile and protein noncoding genes. Therefore, miRNA genes are informational. RNA informational genes (Rigs) can regulate most... -
Genome characteristics of atypical porcine pestivirus from abortion cases in Shandong Province, China
BackgroundAtypical porcine pestivirus (APPV) is a novel, highly variable porcine pestivirus. Previous reports have suggested that the virus is...
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Perceptions and Attitudes Towards Shoulder Padding and Shoulder Injury in Rugby Union
PurposeTo develop an understanding of the role of shoulder padding in rugby union by investigating player perceptions and attitudes towards shoulder...
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Healthy Longevity and Immune System: A Brief Introduction
Since 1990 it has been observed a significant increase of the global aged population with a perspective of 1.5 billion of older individuals by 2050... -
Hepatitis B seroconversion revisited: new insights into the natural history of acute hepatitis B virus (HBV) infection from quantitative and highly sensitive assays and novel biomarkers
BackgroundHepatitis B virus (HBV) serum markers during typical acute self-limited infection are usually depicted as a composite of traditional HBV...
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Fuzzy Mathematical Morphology
In this chapter, we present the theory of fuzzy mathematical morphology, starting from the algebraic notions, the basic operators, and providing some... -
Early and late recurrence after hepatectomy in patients with low-level HBV-DNA hepatocellular carcinoma under antiviral therapy
BackgroundAntiviral therapy has been shown to benefit long-term survival after curative hepatectomy in patients with hepatitis B virus...
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Butyrophilin-like 9 expression is associated with outcome in lung adenocarcinoma
BackgroundLung adenocarcinoma (LUAD) is the most prevalent non-small cell lung cancer (NSCLC). Patients with LUAD have a poor 5-year survival rate....
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Investigations on Sarcocystis species in the leg muscles of the bird family Corvidae in Lithuania
Although three species of Sarcocystis , S . cornixi , S . corvusi and S . kutkienae , have been described in corvids, molecular studies of sarcocysts...
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Repositioning TH cell polarization from single cytokines to complex help
When helper T (T H ) cell polarization was initially described three decades ago, the T H cell universe grew dramatically. New subsets were described...
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Protective Effects of 28-O-Caffeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis
28- O -caffeoyl betulin (B-CA) has been demonstrated to reduce the cerebral infarct volume caused by transient middle cerebral artery occlusion (MCAO)...
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Production and persistence of specific antibodies in COVID-19 patients with hematologic malignancies: role of rituximab
The ability of patients with hematologic malignancies (HM) to develop an effective humoral immune response after COVID-19 is unknown. A prospective...
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Analysis of the HEXA, HEXB, ARSA, and SMPD1 Genes in 68 Iranian Patients
Lysosomal storage diseases (LSDs) are known as genetic disorders with an overall prevalence of 1 per 7700 live births. Sphingolipidosis, which is a...
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Anti-inflammatory polyoxygenated furanocembranoids, salmacembranes A–B from the sea urchin Salmacis bicolor attenuate pro-inflammatory cyclooxygenases and lipoxygenase
Two undescribed polyoxygenated furanocembranoid derivatives, methyl...