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Endothelial dysfunction influences augmented aortic hemodynamic responses to metaboreflex activation in postmenopausal women
PurposePostmenopausal women experience augmented aortic hemodynamic responses to isometric handgrip (IHG) exercise and metaboreflex activation...
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Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India
BackgroundUnderstanding the immune correlates of cardiovascular disease (CVD) risk in HIV infection is an important area of investigation in the...
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Volume elastic modulus with exponential function of transmural pressure as a valid stiffness measure derived by photoplethysmographic volume-oscillometry in human finger and radial arteries: potential for arteriosclerosis screening
Noninvasive and convenient measurement of vascular stiffness is of considerable importance for early detection and treatment of arteriosclerosis....
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Restless legs syndrome, periodic limb movements of sleep, and subclinical cardiovascular disease
Restless legs syndrome (RLS) and periodic limb movements of sleep (PLMS) have been variably implicated in risk for cardiovascular disease (CVD), but...
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Cerebral Small Vessel Disease: a Review of the Pathophysiological Mechanisms
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes involving the brain small vessels and leading to vascular...
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Aortic Valve Calcification Score in Patients with Arterial Hypertension Environmentally Exposed to Tobacco Smoke
The objective of our study was to determine the relationship between exposure to environmental tobacco smoke (ETS) and the value of the aortic valve...
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Effects of Left Ventricular Hypertrophy and Myocardial Stiffness on Myocardial Strain Under Preserved Ejection Fraction
Despite numerous experimental observations regarding heart failure with preserved ejection fraction (HFpEF), which is characterized mainly by left...
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The impact of uninterrupted sitting on central and peripheral cardiovascular function in pre-menopausal and post-menopausal women
Independently, both prolonged uninterrupted sitting and the onset of menopause negatively impact markers of cardiovascular risk. Whether their...
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Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline
BackgroundThe proliferation ability and autophagy level of pulmonary artery endothelial cells (PAECs) play an important role in promoting the...
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Galectin-3 Promotes ROS, Inflammation, and Vascular Fibrosis in Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension (PAH) is a progressive vascular disease arising from the narrowing of pulmonary arteries (PA) resulting in high... -
Left atrial mechanics and aortic stiffness following high intensity interval training: a randomised controlled study
PurposeHigh intensity interval training (HIIT) has been shown to improve important health parameters, including aerobic capacity, blood pressure,...
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Mouse aortic biomechanics are affected by short-term defective autophagy in vascular smooth muscle cells
The physiology of vascular smooth muscle (VSMC) cells is affected by autophagy, a catabolic cellular mechanism responsible for nutrient recycling....
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Empagliflozin ameliorates vascular calcification in diabetic mice through inhibiting Bhlhe40-dependent NLRP3 inflammasome activation
Type 2 diabetes mellitus (T2DM) patients exhibit greater susceptibility to vascular calcification (VC), which has a higher risk of death and...
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Short term e-bicycle riding results in favorable cardiometabolic shifts in moderately active adults
PurposeElectric bikes (EB) are a form of active transportation with demonstrated health benefits. The purpose of this study was to determine the...
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The Effect of Curcumin Supplementation on Pulse Wave Velocity in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Cardiovascular disease is a leading cause of death in many societies. Arterial stiffness is an initial sign of structural and functional changes in... -
Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study
BackgroundIncreased head and neck cancer (HNC) survival requires attention to long-term treatment sequelae. Irradiated HNC survivors have a higher...
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Relationship of anthropometric indices with rate pressure product, pulse pressure and mean arterial pressure among secondary adolescents of 12–17 years
ObjectivesTo determine the correlation between anthropometric indices and the selected hemodynamic parameters among secondary adolescents aged...
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Particle Image Velocimetry to Evaluate Pulse Wave Velocity in Aorta Phantom with the lnD–U Method
PurposePulse wave velocity (PWV) is an indicator of arterial stiffness used in the prediction of cardiovascular disease such as atherosclerosis....
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An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
IntroductionThe neurovascular unit (NVU) – the interaction between the neurons and the cerebrovasculature – is increasingly important to interrogate...
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Acute effects of high-intensity exercise on brain mechanical properties and cognitive function
Previous studies have shown that engagement in even a single session of exercise can improve cognitive performance in the short term. However, the...