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Complementary adenoviral vectors for oncolysis
Replication-competent adenoviruses (Ads) were used for oncolytic virotherapy soon after they were discovered. Recently mutated and genetically...
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Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer
A major obstacle to the success of gene therapy strategies that directly target cancer cells is the poor vector distribution within solid tumors. To...