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Bisphosphonates
Bisphosphonates have been shown to be effective in both increasing bone density and reducing vertebral fracture incidence in post-menopausal...
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Mechanisms of Action of Bisphosphonates as Inhibitors of Bone Resorption
More than 25 years have passed since it was first recognized that bisphosphonates could inhibit bone resorption.1–3 During this time, bisphosphonates... -
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Drug-Food Interactions Affecting Drug Absorption
The intent of this book is to present current information on drug interactions influencing drug absorption, distribution, elimination, and activity.... -
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Treatment of malignant hypercalcaemia with aminohexane bisphosphonate (neridronate)
Twenty patients with hypercalcaemia due to malignancy, which persisted following rehydration, were treated with the bisphosphonate, aminohexane...
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The effects of several diphosphonates on murine bone marrow proliferation
Six diphosphonates were examined for their ability to alter proliferative responses of mouse bone marrow cells to recombinant human M-CSF and...
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Bisphosphonates: Mechanisms of Action and Clinical Use
The bisphosphonates are a new class of drugs which have been developed in the past 2 decades for use in various diseases of bone, tooth, and calcium... -
Paget’s Disease
Paget’s disease is a chronic focal slowly progressive bone disease of unknown aetiology. The first clear description of the disorder was made in 1877...