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Genetic Control of Kidney Morphogenesis
The vertebrate excretory unit, the nephron, is functionally conserved and found in all vertebrates, even dating back to the fossil record (Torrey...
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Aldolase C/zebrin II and the regionalization of the cerebellum
The cerebellum is comprised of multiple bands of cells, each with characteristic afferent and efferent projections, and patterns of gene expression....
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The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry
Since 1971, when W.P. Faulk and G.M. Taylor published “An immunocolloid method for the electron microscope”, colloidal gold has become a very widely...
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Expression of Fǵf-3 in relation to hindbrain segmentation, otic pit position and pharyngeal arch morphology in normal and retinoic acid-exposed mouse embryos
The gene Fgf-3 is expressed in rhombomeres 5 and 6 of the hindbrain and has been functionally implicated in otic development. We describe new sites...
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Protein glycosylation in the endoplasmic reticulum and the Golgi apparatus and cell type-specificity of cell surface glycoconjugate expression: analysis by the protein A-gold and lectin-gold techniques
High resolution immunolabeling applying the protein A-gold technique and carbohydrate cytochemistry using lectin-gold labeling on Lowicryl K4M and...
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Early organization of the pituitary gland in Sparus aurata L. (Teleostei) An ultrastructural study
The cell organization of the pituitary gland and the relationship between neurohypophysis and adenohypophysis in the early developmental stages of...
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Skin-homing T cells in human cutaneous allergic inflammation
The cutaneous lymphocyte-associated antigen (CLA) is a carbohydrate epitope present on memory/effector T cells that infiltrate inflamed skin....
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Axial structures control laterality in the distribution pattern of endothelial cells
In the midline of the embryo an invisible barrier exists that keeps endothelial cells from migrating to the contralateral side. Interspecific...
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Distribution of tripeptidyl-peptidase II in the central nervous system of rat
Tripeptidyl-peptidase II (TPP II) is a high molecular weight serine peptidase which removes tripeptides from a free N-terminus of longer peptides....
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Are region-specific changes in fibre types attributable to nonuniform muscle hypertrophy by overloading?
Muscle fibre composition was compared among the proximal (25%), middle (50%) and distal (75%) regions of the muscle length to investigate whether...
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Glutamine and Cancer Cachexia
The observation that cancer cachexia is associated with specific metabolic abnormalities has stimulated several investigators to attempt to correct...
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Expression of αSM actin in terrestrial ectothermic vertebrates
α-Smooth muscle (αSM) actin of endothermic vertebrates is selectively recognized by the monoclonal antibody anti-αSM-1. Immunoreactivity to this...
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Spinal Cord and Brainstem: Pattern Generators and Reflexes
In this chapter, we shall attempt to look at the elements described in Chap. 49 from a more functional angle and integrate them into a coherent...
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Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed inXenopus laevis oocytes
1. Chronic administration of nicotine up-regulates mammalian neuronal nicotinic acetylcholine receptors (nAChRs). A key hypothesis that explains...
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Pax-1 in the development of the cervico-occipital transitional zone
The Pax-1 gene has been found to play an important role in the development of the vertebral column. The cervico-occipital transitional zone is a...
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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
The expansion of GAG triplet repeats in the translated region of the human HD gene, encoding a protein (huntingtin) of unknown function, is a...
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Experimental analyses of the rearrangement of ectodermal cells during gastrulation and neurulation in avian embryos
The rearrangement of ectodermal cells was studied in chimeras in which grafts were transplanted during late gastrula and early neurula stages to...
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Early stages of chick somite development
We report on the formation and early differentiation of the somites in the avian embryo. The somites are derived from the mesoderm which, in the body...