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Unique Features of the Human Sinoatrial Node Structure, Function, and Arrhythmias: Mechanistic Insights from Integrated 3D Map** Approaches
The sinoatrial node (SAN) is the primary pacemaker in mammalian hearts, which generates intrinsic electrical activation to maintain synchronous and...
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Lecture 20: Anatomy, Structure and Function of Blood Vessels
There are three types of blood vessels: arteries, veins and capillaries. Arteries carry blood away from the heart while veins carry blood to the...
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Structure and function of rice hybrid genomes reveal genetic basis and optimal performance of heterosis
Exploitation of crop heterosis is crucial for increasing global agriculture production. However, the quantitative genomic analysis of heterosis was...
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The Role of Post-Translational Modifications on the Structure and Function of Tau Protein
Involving addition of chemical groups or protein units to specific residues of the target protein, post-translational modifications (PTMs) alter the...
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Structure–Function Relationship of Channelrhodopsins
Ion-translocating rhodopsins, especially channelrhodopsins (ChRs), have attracted broad attention as a powerful tool to modulate the membrane...
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Staphylococcus aureus Virulence Factors and Biofilm Components: Synthesis, Structure, Function and Inhibitors
Staphylococcus aureus is classified as an ESKAPE pathogen, possessing both multi-drug resistance and virulence factors. S. aureus exhibits...
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Enterococcus faecium Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Enterococcus faecium, a Gram-positive bacterium belonging to the family Enterococcaceae is known for its clinical significance due to its ability to...
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Trace amine associated receptor 1: predicted effects of single nucleotide variants on structure-function in geographically diverse populations
Trace Amine Associated Receptor 1 (TAAR1) is a novel pharmaceutical target under investigation for the treatment of several neuropsychiatric...
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Internet addiction-induced brain structure and function alterations: a systematic review and meta-analysis of voxel-based morphometry and resting-state functional connectivity studies
Internet addiction (IA) is a growing social concern and has been intensively studied in recent years. Previous imaging studies have shown that IA may...
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Structure and Mechanism of Function of Botulinum Neurotoxins: How Does the Toxin Work
This chapter discusses the molecular structure of botulinum toxin and how the toxin gets into the nerve cells after being injected into the muscle or...
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Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis
BackgroundMicrobiome-gut-brain axis may be involved in the progression of age-related cognitive impairment and relevant brain structure changes, but...
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Physicochemical properties, molecular structure, antioxidant activity, and biological function of extracellular melanin from Ascosphaera apis
Ascosphaera apis spores containing a dark-colored pigment infect honeybee larvae, resulting in a large-scale collapse of the bee colony due to...
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Map** Structure–Function Relationships within Cerebellar Circuits
A key organizational feature of the cerebellum is its division into a series of cerebellar modules. The cortical component of each module is termed a...
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The Differences in Structure and Function of the Cerebellum Between Cantonese-Mandarin Bilinguals and Mandarin Monolinguals: a Multi-model MRI Study
The effects of the long-term bilingual experience on structure and function of the cerebellum remain unclear. To explore whether there are...
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Strengthening the basics: acids and bases influence vascular structure and function, tissue perfusion, blood pressure, and human cardiovascular disease
Acids and their conjugate bases accumulate in or dissipate from the interstitial space when tissue perfusion does not match the metabolic demand....
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Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2
SARS-CoV-2 has become a global pandemic threatening human health and safety. It is urgent to find effective therapeutic agents and targets with the...
