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State-of-the-Art Review of Advanced Electrospun Nanofiber Composites for Enhanced Wound Healing
Wound healing is a complex biological process with four main phases: hemostasis, inflammation, proliferation, and remodeling. Current treatments such...
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EGFR of platelet regulates macrophage activation and bacterial phagocytosis function
BackgroundBeyond their crucial role in hemostasis, platelets possess the ability to regulate inflammation and combat infections through various...
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Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
ObjectiveThe study was dedicated to investigation of some hemostasis and endothelial dysfunction factors association with probability of presence of...
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Antiplatelets, Anticoagulants, and Fibrinolytics
Primary hemostasis, secondary hemostasis, and fibrinolysis (anticoagulant biological system) are the three distinct-yet-interlinked components of the...
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Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation
Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal...
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Identification and Analysis of DNA Methylation Inflammation-Related Key Genes in Intracerebral Hemorrhage
Inflammation and DNA methylation have been reported to play key roles in intracerebral hemorrhage (ICH). This study aimed to investigate new...
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Assessment of Platelet Function by Automated Light Transmission Aggregometry
Light transmission aggregometry (LTA) has long been the historical “gold standard” of platelet function testing and is typically performed in...
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Pharmacological Correction of Cisplatin-Induced Hemostatic Disorders
A single intraperitoneal administration of cisplatin in the MTD to outbred female mice disturbed hemostasis and formed the procoagulant phenotype of...
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Role of Immune Distribution of Tissue Factor in the Development of Hemostasis during the First Trimester of Normal Pregnancy
Immunohistochemistry of tissue factor, vimentin, and cytokeratin-8 was studied in the medical abortion material at gestation week 5-10 in 20 healthy...
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The Biology of Glial Cells: Recent Advances
This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and...
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Role of Neurons and Glia Cells in Wound Healing as a Novel Perspective Considering Platelet as a Conventional Player
Wound healing is a complex physiological process in which the damaged or injured tissue is replaced or regenerated by new cells or existing cells...
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Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate chemotaxis and leukocyte migration, as well as the...
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The role of regulated necrosis in diabetes and its complications
Morphologically, cell death can be divided into apoptosis and necrosis. Apoptosis, which is a type of regulated cell death, is well tolerated by the...
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Effects of levothyroxine replacement therapy on insulin resistance in patients with untreated primary hypothyroidism
ObjectivesThis study investigated the effects of levothyroxine replacement therapy on insulin resistance, lipid profile, and thyroid function in...
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The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives
The homologous to the E6-AP carboxyl terminus (HECT)-type E3 ubiquitin ligases are the selective executers in the protein ubiquitination, playing a...
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Gut Microbiome in Neurological Health and Disorders
This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in...
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Mechanisms of Hemostasis: Contributions of Platelets, Coagulation Factors, and the Vessel Wall
Hemostasis is a physiological process that allows rapid, localized, and highly regulated closure of an injured blood vessel while maintaining normal...
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Autophagy in Cancer Therapy: Advances and Prospects
Purpose of ReviewAs the primary process involved in regulating cellular hemostasis, autophagy has dual functions in cancer by either promoting or...
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A multisystem, cardio-renal investigation of post-COVID-19 illness
AbstractThe pathophysiology and trajectory of post-Coronavirus Disease 2019 (COVID-19) syndrome is uncertain. To clarify multisystem involvement, we...
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Role and recent progress of P2Y12 receptor in cancer development
P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled receptor (GPCR) that plays a central role in platelet function, hemostasis, and...
