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Intranasal insulin effect on cognitive and/or memory impairment: a systematic review and meta-analysis
Background: Cognitive impairment, characterized by deficits in cognitive functions and loss of delayed and immediate recall, disproportionately...
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Stereotactic Radiotherapy in the Treatment of Prostate Cancer
Stereotactic body radiotherapy (SBRT) is a technologically sophisticated form of radiotherapy and well-established treatment option for patients with...
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The effect of doxorubicin or cyclophosphamide treatment on auditory brainstem response in mice
Clinical studies suggest that chemotherapy is associated with long-term cognitive impairment in some patients. Several underlying mechanisms have...
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Three Days Delayed Recanalization Improved Neurological Function in pMCAO Rats by Increasing M2 Microglia—Possible Involvement of the IL-4R/STAT6/PPARγ Pathway
Current approved therapies for acute ischemic stroke have a restricted therapeutic time window. Delayed recanalization, which has been utilized...
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Corticosterone after early adolescent stress prevents social avoidance, aversive behavior, and morphine-conditioned place preference in adulthood
RationaleStress during childhood or adolescence increases vulnerability to psychiatric disorders in adults. In adult rodents, the delayed effects of...
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Squamous Cell Carcinoma Predisposition Pathophysiology, Diagnosis, and Treatment
Squamous Cell Carcinoma (SCC) is a prevalent form of skin and oral cancer, characterized by the uncontrolled growth of abnormal squamous cells in the...
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Delayed orthostatic hypotension in Parkinson’s disease
Orthostatic hypotension (OH) is relatively common in the early stage of Parkinson’s disease (PD). It is divided into delayed OH and classical OH....
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Serum neurofilament light chain for predicting delayed neurological sequelae after acute carbon monoxide poisoning
IntroductionAcute carbon monoxide (CO) poisoning survivors may experience persistent delayed neurological sequelae (DNS). No studies have...
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Increased blood draws for ultrasensitive ctDNA and CTCs detection in early breast cancer patients
Early breast cancer patients often experience relapse due to residual disease after treatment. Liquid biopsy is a methodology capable of detecting...
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Differences in psychosocial factors and sleep study findings between delayed sleep–wake phase disorder and hypersomnia in teenagers
Central hypersomnia (HS) and delayed sleep–wake phase disorder (DSWPD) appear commonly in adolescents, and they severely reduce quality of life and...
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Post-traumatic syringomyelia resolution following surgical treatment: the moniliform syrinx with a better prognosis
BackgroundPost-traumatic syringomyelia (PTS) presented as a serious delayed complication after spinal cord injury (SCI). In our preliminary...
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Botulinum Toxin Treatment in Children
Over the past 35 years, botulinum toxin therapy in adults has been established as a major mode of treatment for a variety of medical conditions....
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Overcoming challenges to breast cancer screening among Muslim women: addressing barriers to early detection and treatment: A correspondence
Breast cancer is the second leading cause of cancer-related deaths and is the most common type of cancer diagnosed in women. In an attempt to...
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Recombinant Erythropoietin Induces Oligodendrocyte Progenitor Cell Proliferation After Traumatic Brain Injury and Delayed Hypoxemia
Traumatic brain injury (TBI) can result in axonal loss and demyelination, leading to persistent damage in the white matter. Demyelinated axons are...
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Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response
BackgroundZika virus (ZIKV) infection at postnatal or adult age can lead to neurological disorders associated with cognitive defects. Yet, how mature...
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Defining the next generation of severe malaria treatment: a target product profile
BackgroundSevere malaria is a life-threatening infection, particularly affecting children under the age of 5 years in Africa. Current treatment with...
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Effect of four-week cannabidiol treatment on cognitive function: secondary outcomes from a randomised clinical trial for the treatment of cannabis use disorder
RationaleChronic cannabis use is associated with impaired cognitive function. Evidence indicates cannabidiol (CBD) might be beneficial for treating...
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Identification of potential necroinflammation-associated necroptosis-related biomarkers for delayed graft function and renal allograft failure: a machine learning-based exploration in the framework of predictive, preventive, and personalized medicine
Delayed graft function (DGF) is one of the key post-operative challenges for a subset of kidney transplantation (KTx) patients. Graft survival is...
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Mechanism of Biosimilars for the Treatment of Cancer
Biosimilars are biological medications that closely resemble FDA-approved biological medications in terms of structure as well as functions and are...
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Single fraction ablative preoperative radiation treatment for early-stage breast cancer: the CRYSTAL study – a phase I/II clinical trial protocol
BackgroundBreast-conserving surgery (BCS) and whole breast radiation therapy (WBRT) are the standard of care for early-stage breast cancer (BC)....
